Alexandria Marino, MD, PhD

Education

Yale University School of Medicine, New Haven, CT
M.D., cum laude, 2018

Ph.D., Interdepartmental Neuroscience Program, 2016. Dissertation: Perisaccadic updating of attentional state.

Yale University, New Haven, CT
Bachelor of Arts with honors in Cognitive Science, 2005

University of California, Los Angeles, Los Angeles, CA
Certification in secondary science education, 2007

Research Interests and Experience

Grant funding: NIH/NIMH F30MH102010, PI. (Sponsors: James Mazer and Daeyeol Lee)
Neural mechanism of sustained spatial attention across saccades.

Neurophysiology, functional neurosurgery, pediatrics, vascular, vision, resident and patient education

Professional Experience

Teach for America corps member, secondary chemistry educator. Los Angeles, CA, 2005-2007.

University of California, Los Angeles. Research assistant, neuroimaging in schizophrenia, 2007-2008.

Honors

M.D./Ph.D. program graduation award, May 2018

AANS travel award, 2018

Publications

Evolution of Surgical Management of Pineal Region Tumors in the Pediatric Population: A 17-Year Experience at a Single Institution

Pediatr Neurosurg. 2024;59(2-3):66-77. doi: 10.1159/000538745. Epub 2024 Apr 26.ABSTRACTINTRODUCTION: Pineal region tumors have historically been challenging to treat. Advances in surgical techniques have led to significant changes in care and…

Crooke Cell Adenoma Confers Poorer Endocrinological Outcomes Compared with Corticotroph Adenoma: Results of a Multicenter, International Analysis

World Neurosurg. 2023 Dec;180:e376-e391. doi: 10.1016/j.wneu.2023.09.076. Epub 2023 Sep 25.ABSTRACTBACKGROUND: Crooke cell adenomas (CCAs) are a rare, aggressive subset of secretory pituitary corticotroph adenomas (sCTAs) found in 5%-10% of patients…

Defining benchmark outcomes for transsphenoidal surgery of pituitary adenomas: a multicenter analysis

Eur J Endocrinol. 2023 Sep 1;189(3):379-386. doi: 10.1093/ejendo/lvad124.ABSTRACTIMPORTANCE: Benchmarks aid in improve outcomes for surgical procedures. However, best achievable results that have been validated internationally for transsphenoidal surgery (TS) are…

Establishment of Age- and Sex-Specific Reference Cerebral Ventricle Volumes

World Neurosurg. 2023 Jul;175:e976-e983. doi: 10.1016/j.wneu.2023.04.055. Epub 2023 Apr 21.ABSTRACTBACKGROUND: The diagnosis of hydrocephalus is dependent on clinical symptoms and radiographic findings including ventriculomegaly. Our goal was to generate a…

A Multicenter, Propensity Score-Matched Assessment of Endoscopic Versus Microscopic Approaches in the Management of Pituitary Adenomas

Neurosurgery. 2023 Oct 1;93(4):794-801. doi: 10.1227/neu.0000000000002497. Epub 2023 Apr 14.ABSTRACTBACKGROUND AND OBJECTIVES: There is considerable controversy as to which of the 2 operating modalities (microsurgical or endoscopic transnasal surgery) currently…

Melanoma brain metastasis mimicking cortical laminar necrosis

Surg Neurol Int. 2022 Dec 23;13:584. doi: 10.25259/SNI_285_2022. eCollection 2022.ABSTRACTBACKGROUND: Metastatic lesions to the brain are common in patients with melanoma. Imaging characteristics can support the diagnosis of metastatic melanoma,…

Chiari I Malformation and Sleep-Disordered Breathing

Neurosurg Clin N Am. 2023 Jan;34(1):35-41. doi: 10.1016/j.nec.2022.08.005.ABSTRACTSleep-disordered breathing (SDB) is a frequent symptomatic feature of pediatric Chiari I, reported in at least 24% of patients presenting to neurosurgeons. Here…

Revision thoracolumbar surgery for flat back deformity: staged ALIF and posterior column osteotomies to avoid three-column osteotomy

Neurosurg Focus Video. 2020 Jan 1;2(1):V5. doi: 10.3171/2020.1.FocusVid.19740. eCollection 2020 Jan.ABSTRACTThree-column osteotomies (3COs) can achieve significant alignment correction when revising fixed sagittal plane deformities; however, the technique is associated with…

Determining the time frame of maximum clinical improvement in surgical decompression for cervical spondylotic myelopathy when stratified by preoperative myelopathy severity: a cervical Quality Outcomes Database study

J Neurosurg Spine. 2022 Jun 17;37(5):758-766. doi: 10.3171/2022.5.SPINE211425. Print 2022 Nov 1.ABSTRACTOBJECTIVE: While surgical decompression is an important treatment modality for cervical spondylotic myelopathy (CSM), it remains unclear if the…

The effects of avoiding extended antimicrobial drain prophylaxis on Clostridioides difficile and postprocedural infection rates: a 5-year retrospective

J Neurosurg. 2022 Jan 14;137(4):1153-1159. doi: 10.3171/2021.11.JNS211459. Print 2022 Oct 1.ABSTRACTOBJECTIVE: Postprocedural infection is a consequential complication of neurosurgical intervention. Periprocedural antimicrobial prophylaxis is routinely administered to prevent infection, and…

Neurocysticercosis Presenting as an Isolated Suprasellar Lesion

World Neurosurg. 2020 Sep;141:352-356. doi: 10.1016/j.wneu.2020.05.212. Epub 2020 Jun 6.ABSTRACTBACKGROUND: Although extraparenchymal neurocysticercosis (NCC) is well established, presentation in the suprasellar space is rare. When presenting in the suprasellar space,…

Surgery for Pediatric Pituitary Adenomas

Neurosurg Clin N Am. 2019 Oct;30(4):465-471. doi: 10.1016/j.nec.2019.05.008. Epub 2019 Jul 5.ABSTRACTPituitary adenomas are a rare but important central nervous system tumor in children. Because of differences in growth and…

Chiari I malformation in children-the natural history

Childs Nerv Syst. 2019 Oct;35(10):1793-1799. doi: 10.1007/s00381-019-04310-0. Epub 2019 Jul 30.ABSTRACTPURPOSE: To review the natural history of asymptomatic and symptomatic pediatric Chiari I malformations with and without syringomyelia.MATERIALS AND METHODS:…

Resting state connectivity in neocortical epilepsy: The epilepsy network as a patient-specific biomarker

Clin Neurophysiol. 2019 Feb;130(2):280-288. doi: 10.1016/j.clinph.2018.11.016. Epub 2018 Dec 6.ABSTRACTOBJECTIVE: Localization related epilepsy (LRE) is increasingly accepted as a network disorder. To better understand the network specific characteristics of LRE,…

Saccades Trigger Predictive Updating of Attentional Topography in Area V4

Neuron. 2018 Apr 18;98(2):429-438.e4. doi: 10.1016/j.neuron.2018.03.020.ABSTRACTDuring natural behavior, saccades and attention act together to allocate limited neural resources. Attention is generally mediated by retinotopic visual neurons; therefore, specific neurons representing…