Mariam Ishaque, MD, PhD


Doctor of Medicine
University of Texas Health San Antonio, 2018

Doctor of Philosophy
Neuroscience Imaging, Department of Radiological Sciences
University of Texas Health San Antonio, 2016

Bachelor of Science, Physics
Bachelor of Arts, Spanish
Minor, Biological Sciences
Summa cum laude
Southern Methodist University, 2011


Research Interests

Neuroimaging, brain mapping, structural and functional MRI, functional neurosurgery

Research Experience

Department of Neurosurgery, UT Health San Antonio, 2011-2018
Trauma, vascular neurosurgery, functional neurosurgery
Mentors: Ramesh Grandhi, M.D., Alexander Papanastassiou, M.D.

Graduate Research Assistant, UT Health San Antonio, 2013-2016
Dissertation: Investigation of pediatric anoxic brain injury using MRI methods.
Mentor: Peter T. Fox, M.D.

FMRIB Software Library (FSL) Neuroimaging Training Course and Certification, 2015

Imperial College London, London, England, 2015
Functional neurosurgery
Mentor: Dipankar Nandi, M.D., Ph.D.

CERN (Conseil Européen pour la Recherche Nucléaire; European Organization for Nuclear Research), Geneva, Switzerland, 2011-2012
Particle physics: ATLAS and ALICE experiments
Mentors: Michele Floris, Ph.D., Stephen Sekula, Ph.D.


Bilateral focused ultrasound medial thalamotomies for trigeminal neuropathic pain: a randomized controlled study

J Neurosurg. 2023 Dec 29;140(6):1799-1809. doi: 10.3171/2023.10.JNS23661. Print 2024 Jun 1.ABSTRACTOBJECTIVE: Medial thalamotomy has been shown to benefit patients with neuropathic pain, but widespread adoption of this procedure has been…

Long-Term Neurocognitive Outcomes in Pediatric Nonfatal Drowning: Results of a Family Caregiver Survey

Pediatr Neurol. 2024 Feb;151:21-28. doi: 10.1016/j.pediatrneurol.2023.11.001. Epub 2023 Nov 11.ABSTRACTBACKGROUND: Drowning is a leading cause of brain injury in children. Long-term outcome data for drowning survivors are sparse. This study…

Painful Cutaneous Laser Stimulation for Temporal Summation of Pain Assessment

J Pain. 2023 Dec;24(12):2283-2293. doi: 10.1016/j.jpain.2023.07.012. Epub 2023 Jul 17.ABSTRACTVariability in pain sensitivity arises not only from the differences in peripheral sensory receptors but also from the differences in central…

Neurosurgery Subspecialty Practice During a Pandemic: A Multicenter Analysis of Operative Practice in 7 U.S. Neurosurgery Departments During Coronavirus Disease 2019

World Neurosurg. 2022 Sep;165:e242-e250. doi: 10.1016/j.wneu.2022.06.010. Epub 2022 Jun 18.ABSTRACTOBJECTIVE: Changes to neurosurgical practices during the coronavirus disease 2019 (COVID-19) pandemic have not been thoroughly analyzed. We report the effects…

Neuropathology of Parkinson's disease after focused ultrasound thalamotomy

NPJ Parkinsons Dis. 2022 May 12;8(1):59. doi: 10.1038/s41531-022-00319-6.ABSTRACTFocused ultrasound (FUS) thalamotomy is an emerging treatment for tremor-dominant Parkinson's disease (PD). We report the first postmortem neuropathologic study of FUS thalamotomy…

Surface Area of Decompressive Craniectomy Predicts Bone Flap Failure after Autologous Cranioplasty: A Radiographic Cohort Study

Neurotrauma Rep. 2021 Aug 27;2(1):391-398. doi: 10.1089/neur.2021.0015. eCollection 2021.ABSTRACTSkull bone graft failure is a potential complication of autologous cranioplasty after decompressive craniectomy (DC). Our objective was to investigate the association…

Evolution of Surgical Management of Sagittal Synostosis

J Craniofac Surg. 2021 Jan-Feb 01;32(1):155-158. doi: 10.1097/SCS.0000000000007194.ABSTRACTNumerous methods for surgical correction of sagittal synostosis have been described in the literature, yielding similar outcomes. At the authors' institution, surgical approaches…

Case of Lumbar Schwannoma Presenting with Isolated Signs and Symptoms of Intracranial Hypertension

World Neurosurg. 2018 Nov;119:209-214. doi: 10.1016/j.wneu.2018.07.225. Epub 2018 Aug 8.ABSTRACTBACKGROUND: Hydrocephalus and intracranial hypertension are rare signs of spinal tumors when presenting in isolation, particularly with benign tumors.CASE DESCRIPTION: Herein…

Pneumoencephalography in the workup of neuropsychiatric illnesses: a historical perspective

Neurosurg Focus. 2017 Sep;43(3):E10. doi: 10.3171/2017.6.FOCUS17238.ABSTRACTThroughout history, neurosurgical procedures have been fundamental in advancing neuroscience; however, this has not always been without deleterious side effects or harmful consequences. While critical…

Functional integrity in children with anoxic brain injury from drowning

Hum Brain Mapp. 2017 Oct;38(10):4813-4831. doi: 10.1002/hbm.23745. Epub 2017 Jul 31.ABSTRACTDrowning is a leading cause of accidental injury and death in young children. Anoxic brain injury (ABI) is a common…

Lenticulostriate arterial distribution pathology may underlie pediatric anoxic brain injury in drowning

Neuroimage Clin. 2016 Jan 23;11:167-172. doi: 10.1016/j.nicl.2016.01.019. eCollection 2016.ABSTRACTDrowning is a leading cause of neurological morbidity and mortality in young children. Anoxic brain injury (ABI) can result from nonfatal drowning…

Molecular cytogenetics as a clinical test for prognostic and predictive biomarkers in newly diagnosed ovarian cancer

J Ovarian Res. 2013 Jan 4;6(1):2. doi: 10.1186/1757-2215-6-2.ABSTRACTBACKGROUND: There is a clinical need for routinely available genomic biomarker testing in newly diagnosed ovarian cancer. In the current study we performed…