Publications
Current Bielinsky-Hendrickson Publications
Contribution of HMGB1 to Keratinocyte inflammation in Recessive Dystrophic Epidermolysis Bullosa
bioRxiv [Preprint]. 2025 Aug 11:2025.08.11.668806. doi: 10.1101/2025.08.11.668806.ABSTRACTRecessive dystrophic epidermolysis bullosa (RDEB) is an inherited skin disorder characterized by fragile skin, blistering, and chronic wounds. Keratinocytes, the primary cells in the…The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
bioRxiv [Preprint]. 2025 Jul 26:2025.07.24.666583. doi: 10.1101/2025.07.24.666583.ABSTRACTThe activating signal co-integrator 1 complex subunit 3 (ASCC3), the largest subunit of ASCC, is one of two Ski2-like helicases with duplicated helicase cassettes…Gene editing and CRISPR-dependent homology-mediated end joining
Exp Mol Med. 2025 Jul;57(7):1409-1418. doi: 10.1038/s12276-025-01442-z. Epub 2025 Jul 31.ABSTRACTGene editing is the intentional modification of a genetic locus in a living cell and is used for two general…Improved detection of DNA replication fork-associated proteins
Cell Rep. 2024 May 28;43(5):114178. doi: 10.1016/j.celrep.2024.114178. Epub 2024 May 2.ABSTRACTInnovative methods to retrieve proteins associated with actively replicating DNA have provided a glimpse into the molecular dynamics of replication…RNF4 prevents genomic instability caused by chronic DNA under-replication
DNA Repair (Amst). 2024 Mar;135:103646. doi: 10.1016/j.dnarep.2024.103646. Epub 2024 Feb 7.ABSTRACTEukaryotic genome stability is maintained by a complex and diverse set of molecular processes. One class of enzymes that promotes…FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
Cell Rep. 2023 Dec 26;42(12):113523. doi: 10.1016/j.celrep.2023.113523. Epub 2023 Dec 5.ABSTRACTUbiquitination of proliferating cell nuclear antigen (PCNA) at lysine 164 (K164) activates DNA damage tolerance pathways. Currently, we lack a…RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication
Open Biol. 2023 Aug;13(8):230068. doi: 10.1098/rsob.230068. Epub 2023 Aug 23.ABSTRACTDNA replication requires precise regulation achieved through post-translational modifications, including ubiquitination and SUMOylation. These modifications are linked by the SUMO-targeted E3…Publications (10 years) Prior to 2023
(For a complete list of publications)
https://pubmed.ncbi.nlm.nih.gov/?term=Bielinsky+AK&sort=date
2022
Lin, K., Chang, Y. -C., de Velasco, E. M. F., Wickman, K., Myers, C. L., & Bielinsky, A. -K. (2022). Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells. STAR PROTOCOLS, 3(4). doi:10.1016/j.xpro.2022.101675
Grange, L. J., Reynolds, J. J., Ullah, F., Isidor, B., Shearer, R. F., Latypova, X., . . . Stewart, G. S. (2022). Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-34349-8
2021
Okamoto, Y., Abe, M., Mu, A., Tempaku, Y., Rogers, C. B., Mochizuki, A. L., . . . Takata, M. (2021). SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells. BLOOD, 137(3), 336-348. doi:10.1182/blood.2019003782
Baxley, R. M., Leung, W., Schmit, M. M., Matson, J. P., Yin, L., Oram, M. K., . . . Bielinsky, A. -K. (2021). Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-21878-x
Kang, Z., Fu, P., Alcivar, A. L., Fu, H., Redon, C., Foo, T. K., . . . Xia, B. (2021). BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-26227-6
Schmit, M., & Bielinsky, A. -K. (2021). Congenital Diseases of DNA Replication: Clinical Phenotypes and Molecular Mechanisms. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(2). doi:10.3390/ijms22020911
Chang, Y. -C., Oram, M. K., & Bielinsky, A. -K. (2021). SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(10). doi:10.3390/ijms22105391
2020
Mace, E. M., Paust, S., Conte, M. I., Baxley, R. M., Schmit, M. M., Patil, S. L., . . . Orange, J. S. (2020). Human NK cell deficiency as a result of biallelic mutations in MCM10. JOURNAL OF CLINICAL INVESTIGATION, 130(10), 5272-5286. doi:10.1172/JCI134966
Raghunandan, M., Yeo, J. E., Walter, R., Saito, K., Harvey, A. J., Ittershagen, S., . . . Sobeck, A. (2020). Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery. HUMAN MOLECULAR GENETICS, 29(7), 1083-1095. doi:10.1093/hmg/ddz250
Thakar, T., Leung, W., Nicolae, C. M., Clements, K. E., Shen, B., Bielinsky, A. -K., & Moldovan, G. -L. (2020). Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-16096-w
Stroik, S., Kurtz, K., Lin, K., Karachenets, S., Myers, C. L., Bielinsky, A. -K., & Hendrickson, E. A. (2020). EXO1 resection at G-quadruplex structures facilitates resolution and replication. NUCLEIC ACIDS RESEARCH, 48(9), 4960-4975. doi:10.1093/nar/gkaa199
2019
Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., . . . Cook, J. G. (2019). Correction: Rapid DNA replication origin licensing protects stem cell pluripotency.. eLife, 8, e49040. doi:10.7554/elife.49040
Leung, W., Baxley, R. M., Moldovan, G. -L., & Bielinsky, A. -K. (2019). Mechanisms of DNA Damage Tolerance: Post-Translational Regulation of PCNA. GENES, 10(1). doi:10.3390/genes10010010
Paulson, C. N., John, K., Baxley, R. M., Kurniawan, F., Orellana, K., Francis, R., . . . Bielinsky, A. -K. (2019). The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10. OPEN BIOLOGY, 9(8). doi:10.1098/rsob.190117
2018
Becker, J. R., Gallo, D., Leung, W., Croissant, T., Thu, Y. M., Hai, D. N., . . . Bielinsky, A. -K. (2018). Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner. NUCLEIC ACIDS RESEARCH, 46(11), 5634-5650. doi:10.1093/nar/gky313
Kurniawan, F., Shi, K., Kurahashi, K., Bielinsky, A. -K., & Aihara, H. (2018). Crystal Structure of Entamoeba histolytica Cdc45 Suggests a Conformational Switch that May Regulate DNA Replication. ISCIENCE, 3, 102-+. doi:10.1016/j.isci.2018.04.011
2017
Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., . . . Cook, J. G. (2017). Rapid DNA replication origin licensing protects stem cell pluripotency. ELIFE, 6. doi:10.7554/eLife.30473
Baxley, R. M., & Bielinsky, A. -K. (2017). Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks. GENES, 8(2). doi:10.3390/genes8020073
2016
Zhang, T., Fultz, B. L., Das-Bradoo, S., & Bielinsky, A. -K. (2016). Mapping ubiquitination sites of S. cerevisiae Mcm10.. Biochemistry and biophysics reports, 8, 212-218. doi:10.1016/j.bbrep.2016.09.003
Bielinsky, A. -K. (2016). Mcm10: The glue at replication forks. CELL CYCLE, 15(22), 3024-3025. doi:10.1080/15384101.2016.1216925
Thu, Y. M., Van Riper, S. K., Higgins, L., Zhang, T., Becker, J. R., Markowski, T. W., . . . Bielinsky, A. K. (2016). Slx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic Progression. CELL REPORTS, 15(6), 1254-1265. doi:10.1016/j.celrep.2016.04.017
Bielinsky, A. -K., & Leung, W. (2016). Not just for coding: a new role for histone tails in replication enzyme activation. FEBS Journal, 283(23), 4244-4246. doi:10.1111/febs.13958
2015
Avdulov, S., Herrera, J., Smith, K., Peterson, M., Gomez-Garcia, J. R., Beadnell, T. C., . . . Polunovsky, V. A. (2015). eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells. CANCER RESEARCH, 75(4), 687-697. doi:10.1158/0008-5472.CAN-14-2571
Becker, J. R., Pons, C., Hai, D. N., Costanzo, M., Boone, C., Myers, C. L., & Bielinsky, A. -K. (2015). Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing. PLOS GENETICS, 11(11). doi:10.1371/journal.pgen.1005659
Bielinsky, A. -K. (2015). Penetrating enemy territory: Soluble PCNA-peptides stress out MYCN-overexpressing neuroblastomas. EBIOMEDICINE, 2(12), 1844-1845. doi:10.1016/j.ebiom.2015.12.012
2014
Thu, Y. M., & Bielinsky, A. -K. (2014). MCM10: One tool for all-Integrity, maintenance and damage control. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 30, 121-130. doi:10.1016/j.semcdb.2014.03.017
Alver, R. C., Zhang, T., Josephrajan, A., Fultz, B. L., Hendrix, C. J., Das-Bradoo, S., & Bielinsky, A. -K. (2014). The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage. NUCLEIC ACIDS RESEARCH, 42(13), 8389-8404. doi:10.1093/nar/gku479
Becker, J. R., Hai, D. N., Wang, X., & Bielinsky, A. -K. (2014). Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair. CELL CYCLE, 13(11). doi:10.4161/cc.28652
2013
Du, W., Josephrajan, A., Adhikary, S., Bowles, T., Bielinsky, A. -K., & Eichman, B. F. (2013). Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain. PLOS ONE, 8(7). doi:10.1371/journal.pone.0070518
Nguyen, H. D., Becker, J., Thu, Y. M., Costanzo, M., Koch, E. N., Smith, S., . . . Bielinsky, A. -K. (2013). Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression. PLOS ONE, 8(6). doi:10.1371/journal.pone.0066379
Ragland, R. L., Patel, S., Rivard, R. S., Smith, K., Peters, A. A., Bielinsky, A. -K., & Brown, E. J. (2013). RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells. GENES & DEVELOPMENT, 27(20), 2259-2273. doi:10.1101/gad.223180.113
Thu, Y. M., & Bielinsky, A. -K. (2013). Enigmatic roles of Mcm10 in DNA replication. TRENDS IN BIOCHEMICAL SCIENCES, 38(4), 184-194. doi:10.1016/j.tibs.2012.12.003
(For a complete list of publications)
https://pubmed.ncbi.nlm.nih.gov/?term=Hendrickson+EA&sort=date
2022
Liddiard, K., Aston-Evans, A. N., Cleal, K., Hendrickson, E. A., & Baird, D. M. (2022). POLQ suppresses genome instability and alterations in DNA repeat tract lengths. NAR CANCER, 4(3). doi:10.1093/narcan/zcac020
Geiller, H. E. B., Harvey, A., Jones, R. E., Grimstead, J. W., Cleal, K., Hendrickson, E. A., & Baird, D. M. (2022). ATRX modulates the escape from a telomere crisis. PLOS GENETICS, 18(11). doi:10.1371/journal.pgen.1010485
2021
Baxley, R. M., Leung, W., Schmit, M. M., Matson, J. P., Yin, L., Oram, M. K., . . . Bielinsky, A. -K. (2021). Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-21878-x
2020
Stroik, S., & Hendrickson, E. A. (2020). Telomere fusions and translocations: a bridge too far?. CURRENT OPINION IN GENETICS & DEVELOPMENT, 60, 85-91. doi:10.1016/j.gde.2020.02.010
Hendrickson, E. A. (2020). RAD52: Viral Friend or Foe?. CANCERS, 12(2). doi:10.3390/cancers12020399
Ruis, B., Molan, A., Takasugi, T., & Hendrickson, E. A. (2020). Absence of XRCC4 and its paralogs in human cells reveal differences in outcomes for DNA repair and V(D)J recombination. DNA REPAIR, 85. doi:10.1016/j.dnarep.2019.102738
Ferrer, A., Mangaonkar, A. A., Stroik, S., Zimmermann, M. T., Sigafoos, A. N., Kamath, P. S., . . . Patnaik, M. M. (2020). Functional validation of TERT and TERC variants of uncertain significance in patients with short telomere syndromes. BLOOD CANCER JOURNAL, 10(11). doi:10.1038/s41408-020-00386-z
Stroik, S., & Hendrickson, E. A. (2020). Telomere replication-When the going gets tough. DNA REPAIR, 94. doi:10.1016/j.dnarep.2020.102875
Raghunandan, M., Yeo, J. E., Walter, R., Saito, K., Harvey, A. J., Ittershagen, S., . . . Sobeck, A. (2020). Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery. HUMAN MOLECULAR GENETICS, 29(7), 1083-1095. doi:10.1093/hmg/ddz250
Stroik, S., Kurtz, K., Lin, K., Karachenets, S., Myers, C. L., Bielinsky, A. -K., & Hendrickson, E. A. (2020). EXO1 resection at G-quadruplex structures facilitates resolution and replication. NUCLEIC ACIDS RESEARCH, 48(9), 4960-4975. doi:10.1093/nar/gkaa199
2019
Liddiard, K., Ruis, B., Kan, Y., Cleal, K., Ashelford, K. E., Hendrickson, E. A., & Baird, D. M. (2019). DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase. NUCLEIC ACIDS RESEARCH, 47(5), 2402-2424. doi:10.1093/nar/gky1279
Cleal, K., Jones, R. E., Grimstead, J. W., Hendrickson, E. A., & Baird, D. M. (2019). Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. GENOME RESEARCH, 29(5), 737-749. doi:10.1101/gr.240705.118
Nera, B., Huang, H. -S., Hendrickson, E. A., & Xu, L. (2019). Both the classical and alternative non-homologous end joining pathways contribute to the fusion of drastically shortened telomeres induced by TRF2 overexpression. CELL CYCLE, 18(8), 880-888. doi:10.1080/15384101.2019.1598724
Kan, Y., & Hendrickson, E. A. (2019). Conversion Tract Analysis of Homology-Directed Genome Editing Using Oligonucleotide Donors. DNA REPAIR: METHODS AND PROTOCOLS, 1999, 131-144. doi:10.1007/978-1-4939-9500-4_7
Lu, H., Saha, J., Beckmann, P. J., Hendrickson, E. A., & Davis, A. J. (2019). DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response. NUCLEIC ACIDS RESEARCH, 47(18), 9467-9479. doi:10.1093/nar/gkz694
Stroik, S., Kurtz, K., & Hendrickson, E. A. (2019). NAR Breakthrough Article CtIP is essential for telomere replication. NUCLEIC ACIDS RESEARCH, 47(17), 8927-8940. doi:10.1093/nar/gkz652
2018
Ngo, G., Hyatt, S., Grimstead, J., Jones, R., Hendrickson, E., Pepper, C., & Baird, D. (2018). PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation.. Oncotarget, 9(101), 37549-37563. doi:10.18632/oncotarget.26499
Harvey, A., Mielke, N., Grimstead, J. W., Jones, R. E., Nguyen, T., Mueller, M., . . . Hendrickson, E. A. (2018). PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ.. Oncotarget, 9(78), 34821-34837. doi:10.18632/oncotarget.26201
Baird, D. M., & Hendrickson, E. A. (2018). Telomeres and Chromosomal Translocations There’s a Ligase at the End of the Translocation. CHROMOSOME TRANSLOCATION, 1044, 89-112. doi:10.1007/978-981-13-0593-1_7
Li, G., Martinez-Bonet, M., Wu, D., Yang, Y., Cui, J., Nguyen, H. N., . . . Nigrovic, P. A. (2018). High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. NATURE GENETICS, 50(8), 1180-+. doi:10.1038/s41588-018-0159-z
Gu, P., Jia, S., Takasugi, T., Smith, E., Nandakumar, J., Hendrickson, E., & Chang, S. (2018). CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. AGING CELL, 17(4). doi:10.1111/acel.12783
Kawale, A. S., Akopiants, K., Valerie, K., Ruis, B., Hendrickson, E. A., Huang, S. -Y. N., . . . Povirk, L. F. (2018). TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining. NUCLEIC ACIDS RESEARCH, 46(17), 8926-8939. doi:10.1093/nar/gky694
2017
Kan, Y., Batada, N. N., & Hendrickson, E. A. (2017). Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair. DNA REPAIR, 55, 64-75. doi:10.1016/j.dnarep.2017.04.006
Kan, Y., Ruis, B., Takasugi, T., & Hendrickson, E. A. (2017). Mechanisms of precise genome editing using oligonucleotide donors. GENOME RESEARCH, 27(7), 1099-1111. doi:10.1101/gr.214775.116
Thompson, E. L., Yeo, J. E., Lee, E. -A., Kan, Y., Raghunandan, M., Wiek, C., . . . Sobeck, A. (2017). FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. NUCLEIC ACIDS RESEARCH, 45(20), 11837-11857. doi:10.1093/nar/gkx847
2016
Liddiard, K., Ruis, B., Takasugi, T., Harvey, A., Ashelford, K. E., Hendrickson, E. A., & Baird, D. M. (2016). Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4. GENOME RESEARCH, 26(5), 588-600. doi:10.1101/gr.200840.115
Neal, J. A., Xu, Y., Abe, M., Hendrickson, E., & Meek, K. (2016). Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining. JOURNAL OF IMMUNOLOGY, 196(7), 3032-3042. doi:10.4049/jimmunol.1501654
Alotaibi, M., Sharma, K., Saleh, T., Povirk, L. F., Hendrickson, E. A., & Gewirtz, D. A. (2016). Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells. RADIATION RESEARCH, 185(3), 229-245. doi:10.1667/RR14202.1
2015
Thangavel, S., Berti, M., Levikova, M., Pinto, C., Gomathinayagam, S., Vujanovic, M., . . . Vindigni, A. (2015). DNA2 drives processing and restart of reversed replication forks in human cells.. The Journal of cell biology, 208(5), 545-562. doi:10.1083/jcb.201406100
Hendrickson, E. A., & Baird, D. M. (2015). Alternative end joining, clonal evolution, and escape from a telomere-driven crisis. MOLECULAR & CELLULAR ONCOLOGY, 2(1). doi:10.4161/23723556.2014.975623
Batenburg, N. L., Thompson, E. L., Hendrickson, E. A., & Zhu, X. -D. (2015). Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO JOURNAL, 34(10), 1399-1416. doi:10.15252/embj.201490041
Li, Y., Park, A. I., Mou, H., Colpan, C., Bizhanova, A., Akama-Garren, E., . . . Xue, W. (2015). A versatile reporter system for CRISPR-mediated chromosomal rearrangements. GENOME BIOLOGY, 16. doi:10.1186/s13059-015-0680-7
Napier, C. E., Huschtscha, L. I., Harvey, A., Bower, K., Noble, J. R., Hendrickson, E. A., & Reddel, R. R. (2015). ATRX represses alternative lengthening of telomeres. ONCOTARGET, 6(18), 16543-16558. doi:10.18632/oncotarget.3846
Castella, M., Jacquemont, C., Thompson, E. L., Yeo, J. E., Cheung, R. S., Huang, J. -W., . . . Taniguchi, T. (2015). FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2. PLoS Genetics, 11(10). doi:10.1371/journal.pgen.1005563
Roy, S., de Melo, A. J., Xu, Y., Tadi, S. K., Negrel, A., Hendrickson, E., . . . Meek, K. (2015). XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation. MOLECULAR AND CELLULAR BIOLOGY, 35(17), 3017-3028. doi:10.1128/MCB.01503-14
2014
Smith, S., Fox, J., Mejia, M., Ruangpradit, W., Saberi, A., Kim, S., . . . Myung, K. (2014). Histone Deacetylase Inhibitors Selectively Target Homology Dependent DNA Repair Defective Cells and Elevate Non-Homologous Endjoining Activity. PLOS ONE, 9(1). doi:10.1371/journal.pone.0087203
Fattah, F. J., Kweon, J., Wang, Y., Lee, E. H., Kan, Y., Lichter, N., . . . Hendrickson, E. A. (2014). A role for XLF in DNA repair and recombination in human somatic cells. DNA REPAIR, 15, 39-53. doi:10.1016/j.dnarep.2013.12.006
Yeo, J. E., Lee, E. H., Hendrickson, E. A., & Sobeck, A. (2014). CtIP mediates replication fork recovery in a FANCD2-regulated manner. HUMAN MOLECULAR GENETICS, 23(14), 3695-3705. doi:10.1093/hmg/ddu078
Karanja, K. K., Lee, E. H., Hendrickson, E. A., & Campbell, J. L. (2014). Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells. CELL CYCLE, 13(10), 1540-1550. doi:10.4161/cc.28476
Oh, S., Harvey, A., Zimbric, J., Wang, Y., Thanh, N., Jackson, P. J., & Hendrickson, E. A. (2014). DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells. DNA REPAIR, 21, 97-110. doi:10.1016/j.dnarep.2014.04.015
Kan, Y., Ruis, B., Lin, S., & Hendrickson, E. A. (2014). The Mechanism of Gene Targeting in Human Somatic Cells. PLOS GENETICS, 10(4). doi:10.1371/journal.pgen.1004251
Waters, C. A., Strande, N. T., Pryor, J. M., Strom, C. N., Mieczkowski, P., Burkhalter, M. D., . . . Ramsden, D. A. (2014). The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining. NATURE COMMUNICATIONS, 5. doi:10.1038/ncomms5286
Ghezraoui, H., Piganeau, M., Renouf, B., Renaud, J. -B., Sallmyr, A., Ruis, B., . . . Brunet, E. (2014). Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining. MOLECULAR CELL, 55(6), 829-842. doi:10.1016/j.molcel.2014.08.002
Jones, R. E., Oh, S., Grimstead, J. W., Zimbric, J., Roger, L., Heppel, N. H., . . . Baird, D. M. (2014). Escape from Telomere-Driven Crisis Is DNA Ligase III Dependent. CELL REPORTS, 8(4), 1063-1076. doi:10.1016/j.celrep.2014.07.007
2013
Yang, Y., Durando, M., Smith-Roe, S. L., Sproul, C., Greenwalt, A. M., Kaufmann, W., . . . Vaziri, C. (2013). Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. NUCLEIC ACIDS RESEARCH, 41(4), 2296-2312. doi:10.1093/nar/gks1325
Oh, S., Wang, Y., Zimbric, J., & Hendrickson, E. A. (2013). Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction. NUCLEIC ACIDS RESEARCH, 41(3), 1734-1749. doi:10.1093/nar/gks1326