UVA Testing New Treatment for Enlarged Prostate Symptoms

January 25, 2016 by School of Medicine Webmaster   |   Leave a Comment

University of Virginia Health System researchers have opened a national clinical trial examining a non-surgical treatment for lower urinary tract symptoms caused by an enlarged prostate.

Also known as benign prostatic hyperplasia, or BPH, an enlarged prostate is a common condition unrelated to cancer that affects about 210 million men worldwide, according to researchers from UVA’s Division of Interventional Radiology and Department of Urology. By age 80, nine of 10 men have an enlarged prostate, with half of these men experiencing symptoms. Symptoms can include frequent urination, painful urination, an urgent need to urinate, excessive nighttime urination, weak urine stream and incomplete emptying of the bladder.

UVA is among a few sites in the U.S. examining the safety and effectiveness of a procedure called prostatic artery embolization, or PAE. Pioneered by interventional radiologists in Europe and Latin America, the treatment may provide a potential alternative to other available invasive surgical treatments.

During a PAE procedure, doctors make a tiny nick in the groin and guide a small tube called a microcatheter into the small arteries that supply the prostate with blood. Microparticles are injected into the arteries to block blood flow to the prostate, with the goal of shrinking the prostate and improving unpleasant urinary symptoms.

“We’re excited to study this nonsurgical option for prostate symptoms, hopefully sparing men the risks of incontinence and sexual dysfunction, in the setting of this U.S. Food and Drug Administration-monitored clinical study,” said Dr. Ziv J. Haskal, the trial’s principal investigator and a Professor of Radiology at the UVA School of Medicine.

Data from the largest clinical trial to date reported sustained improvement in symptoms for 72 percent of men three years after receiving the investigational treatment.

Researchers expect to enroll 50 to 80 men, ages 45 to 80, with symptoms due to BPH who are not responding to medications or do not wish to be treated with surgery or medications.

Anyone interested in participating in this study should contact Brigitte Kelly at 434-297-7136 or The trial is IRB No. 18236.

More information about the trial is available here.

Source: UVA Today, November 30, 2015, Jessica Lukens, 



Comments (3)

  1. Laurie says:

    I think that is is wonderful that testing is being done as alternate treatments for prostate symptoms and that the results are looking promising. Keep up the good work, thanks for sharing!

    1. Brigitte Kelly says:

      Hi Laurie-
      Thank you for the positive note and words of encouragement! Our research team believes this to be a very promising non-surgical alternative to relieving lower urinary tract symptoms.
      While I see your products, Men’s Liberty, primarily deal with incontinence, we would be delighted if you were interested in sharing our press release in your blog space. Our feedback from men’s health sites has been amazing! I have learned there are many men who suffer in silence and look to sites like yours for help.
      I would be happy to chat with you offline to explore ways that we can work together to reach men who could potentially be interested in participating in this important research.


  2. Bobby Taylor says:

    How can I find a really competent interventional radiologist who know this procedure?. My kindness are being affected by limited urine flow likely backing up into the kidneys. Have BPH, will travel!

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