Services
Biospecimen procurement, processing & banking
- Human tissue procurement from clinical specimens and preservation
- Surgical resection specimens (targeted collection of remnant material)
- Autopsy specimens (targeted collection of remnant material)
- Study-specific collection of non-remnant material (consented)
- Banked specimens for future research (>30,000 specimens available)
- Biofluid sample processing
- Clinical trial support (processing, logistics, shipping)
- Processing for other investigator-initiated studies
- Pickup from UVA Health System Hospital and clinics
- For information on phlebotomy services click here
- Enzymatic dissociation & viable freezing of tissue samples
- Peripheral blood leukocyte (PBL) Ficoll isolation & viable freezing
- Extraction of nucleic acids and protein from tissue samples including microcapillary electrophoresis and RNA amplification & labeling
Histology-based research techniques
For basic histology services (processing/embedding/sectioning) involving animal tissues, please use the Research Histology Core Facility. The BTRF does accept animal tissues for IHC, CISH, laser microdissection, and other advanced applications.
- Paraffin embedding of human tissue specimens
- Histologic sectioning of fixed human tissue specimens
- Cryostat sectioning of frozen human tissue specimens
- Training on instrument
- Equipment usage
- Cytospin preparation of fluids containing cells
- Histology-guided macrodissection to enrich for specific cell types
- Laser microdissection
- Training on instrument
- Equipment usage
- Immunohistochemistry (IHC)
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- Performed on human and animal tissues
- Panel of “standard” antibodies (for more information click here)
- Custom immunohistochemistry (Investigator-supplied antibody)
- chromogenic RNA in situ hybridization (CISH)
- Custom tissue microarray manufacture
- Tissue microarray of the most common human carcinomas (159 cases)