Publications
Th17 Cells in Parkinson's Disease: The Bane of the Midbrain.
Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism.
Publication:
Journal of Immunology
Authors:
Catherine R. Lammert, Elizabeth L. Frost, Ashley C. Bolte, Matt J. Paysour, Mariah E. Shaw, Calli E. Bellinger, Thaddeus K. Weigel, Eli R. Zunder, John R. Lukens.
NLR-Dependent Regulation of Inflammation in Multiple Sclerosis.
Publication:
Frontiers in Immunology
Authors:
Marjan Gharagozloo, Katsiaryna V. Gris, Tara Mahvelati, Abdelaziz Amrani, John R. Lukens, and Denis Gris.
Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.
Publication:
Journal of Immunology
Authors:
Jillian P. Rhoads, John R. Lukens, Ashley J. Wilhelm, Jared L. Moore, Yanice Mendez-Fernandez, Thirumala-Devi Kanneganti and Amy S. Major.
Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.
Publication:
Immunity
Authors:
Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K. Tonks, Thirumala-Devi Kanneganti.
Emerging Roles for the Immune System in Traumatic Brain Injury.
The Brain’s Reward Circuitry Regulates Immunity.
Dealing with Danger in the CNS: The Response of the Immune System to Injury.
Publication:
Neuron
Authors:
Sachin P. Gadani, James T. Walsh, John R. Lukens, Jonathan Kipnis.
The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.
Publication:
Immunity
Authors:
Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD.
Dietary modulation of the microbiome affects autoinflammatory disease.
Publication:
Nature
Authors:
Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD.
RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.
Publication:
Nature
Authors:
Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD.
Critical role for inflammasome-independent IL-1β production in osteomyelitis.
Publication:
Proceedings of the National Academy of Sciences USA
Authors:
Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD.
Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells.
Publication:
The Journal of Immunology
Authors:
Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD.
Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease.
IL-1 family cytokines trigger sterile inflammatory disease.
Publication:
Frontiers in Immunology
Authors:
Lukens JR, Gross JM, Kanneganti TD.