Bhargav Desai, MD

Education

M.D., with distinction, Chicago Medical School at the Rosalind Franklin University, 2017

Bachelor of Science, Biomedical Engineering, University of Illinois at Chicago, 2012

Research Interests: Movement disorders, Epilepsy, Spine

Honors

Junior election to Alpha Omega Alpha Honor Medical Society, 2016
2016 – Chicago Medical School, Summer Research Fellowship Travel Award

Publications

The recent advances in cobalt-catalyzed C(sp3)-H functionalization reactions

Org Biomol Chem. 2023 Jan 25;21(4):673-699. doi: 10.1039/d2ob01936a.ABSTRACTOver the past decades, reactions involving C-H functionalization have become a hot theme in organic transformations because they have a lot of potential…

Recent advances in visible-light-mediated functionalization of olefins and alkynes using copper catalysts

Chem Commun (Camb). 2022 Jul 14;58(57):7850-7873. doi: 10.1039/d2cc01611g.ABSTRACTOver the past decade, visible-light photoredox catalysis has blossomed as a powerful strategy and offers a discrete activation mode complementary to thermal controlled…

FGFR1-TACC1 fusion associated with malignant transformation in a primary spinal cord glioma: a case report

J Spine Surg. 2021 Sep;7(3):434-438. doi: 10.21037/jss-21-24.ABSTRACTMolecular mechanisms of malignant transformation in spinal cord gliomas are not well-understood. Our objective was to investigate genetic causes of malignant transformation in a…

Recent advances in directed sp2 C-H functionalization towards the synthesis of N-heterocycles and O-heterocycles

Chem Commun (Camb). 2021 Sep 11;57(70):8699-8725. doi: 10.1039/d1cc02176a. Epub 2021 Aug 16.ABSTRACTHeterocyclic compounds are widely present in the core structures of several natural products, pharmaceuticals and agrochemicals, and thus great…

Erratum to Evaluating the safety and efficacy of various endovascular approaches for the treatment of infectious intracranial aneurysms: a systematic review. World Neurosurgery. Volume 144, December 2020, Pages 293-298.e15

World Neurosurg. 2021 Aug;152:255-275. doi: 10.1016/j.wneu.2020.12.052. Epub 2021 Apr 28.ABSTRACTOBJECTIVE: A review of endovascular cerebral mycotic aneurysm treatment with Onyx liquid embolic, N-butyl-2-cyanoacrylate (NBCA), or coil embolization has not been…

A Systematic Review of the Cost-Utility of Spinal Cord Stimulation for Persistent Low Back Pain in Patients With Failed Back Surgery Syndrome

Global Spine J. 2021 Apr;11(1_suppl):66S-72S. doi: 10.1177/2192568220970163.ABSTRACTSTUDY DESIGN: Systematic Review.OBJECTIVES: To review the literature surrounding the cost-effectiveness of implanting spinal cord stimulators for failed back surgery syndrome.METHODS: A systematic review…

Diagnostic, Surgical, and Technical Considerations for Lumbar Interbody Fusion in Patients with Osteopenia and Osteoporosis: A Systematic Review

Brain Sci. 2021 Feb 14;11(2):241. doi: 10.3390/brainsci11020241.ABSTRACTOBJECTIVE: Osteoporosis is increasing in incidence as the ageing population continues to grow. Decreased bone mineral density poses a challenge for the spine surgeon.…

A single-center retrospective analysis of 3- or 4-level anterior cervical discectomy and fusion: surgical outcomes in 66 patients

J Neurosurg Spine. 2020 Oct 9:1-7. doi: 10.3171/2020.6.SPINE20171. Online ahead of print.ABSTRACTOBJECTIVE: Anterior cervical discectomy and fusion (ACDF) is a safe and effective intervention to treat cervical spine pathology. Although…

Evaluating the Safety and Efficacy of Various Endovascular Approaches for Treatment of Infectious Intracranial Aneurysms: A Systematic Review

World Neurosurg. 2020 Dec;144:293-298.e15. doi: 10.1016/j.wneu.2020.07.228. Epub 2020 Aug 17.ABSTRACTOBJECTIVE: A review of endovascular cerebral mycotic aneurysm treatment with Onyx liquid embolic, N-butyl-2-cyanoacrylate (NBCA), or coil embolization has not been…

Pharmacologic considerations in patients with osteoporosis undergoing lumbar interbody fusion: A systematic review

Clin Neurol Neurosurg. 2020 Sep;196:106030. doi: 10.1016/j.clineuro.2020.106030. Epub 2020 Jun 25.ABSTRACTOBJECTIVE: As the ageing population continues to grow, the incidence of osteoporosis continues to rise. Patients with osteoporosis are often…

Clinical and radiographic adverse events after Gamma Knife radiosurgery for brainstem lesions: A dosimetric analysis

Radiother Oncol. 2020 Jun;147:200-209. doi: 10.1016/j.radonc.2020.05.010. Epub 2020 May 13.ABSTRACTOBJECTIVES: To analyze the association between dosvolume relationships and adverse events in brainstem lesions treated with Gamma Knife radiosurgery (GKRS).METHODS: Treatment…

Cortical Spreading Depression in the Setting of Traumatic Brain Injury

World Neurosurg. 2020 Feb;134:50-57. doi: 10.1016/j.wneu.2019.10.048. Epub 2019 Oct 23.ABSTRACTCortical spreading depression (CSD) is a pathophysiologic phenomenon that describes an expanding wave of depolarization within the cortical gray matter. Originally…

Surgery for Pediatric Pituitary Adenomas

Neurosurg Clin N Am. 2019 Oct;30(4):465-471. doi: 10.1016/j.nec.2019.05.008. Epub 2019 Jul 5.ABSTRACTPituitary adenomas are a rare but important central nervous system tumor in children. Because of differences in growth and…

Giant Thoracic Calcified Disk: Conservative Management with 3-Year Follow-Up

World Neurosurg. 2019 May;125:1-2. doi: 10.1016/j.wneu.2019.01.083. Epub 2019 Jan 28.ABSTRACTCalcified disk herniation of the thoracic spine is by no means a rare clinical entity in neurosurgery. We present a 63-year-old…

Utility of topical tranexamic acid for adult patients with spinal deformity and contraindications to systemic tranexamic acid: initial experience and report of 2 cases

J Neurosurg Spine. 2019 Jan 25:1-6. doi: 10.3171/2018.9.SPINE18204. Online ahead of print.ABSTRACTTranexamic acid (TXA) is an antifibrinolytic agent with demonstrated efficacy in reducing blood loss when administered systemically. However, in…