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Experimental Pathology

About

Four different kinds of cells magnifiedThe Molecular and Cellular Basis of Disease (MCBD) graduate program confers the PhD in Experimental Pathology.  The program is designed for students with a research interest in the mechanisms of human disease processes, with a particular emphasis on the skills necessary to perform translational research. In addition to basic laboratory skills, the program offers the opportunity for collaborative work with top-ranked and internationally recognized pathologists and other clinicians as part of PhD training. These experiences provide our trainees with an understanding of modern medical problems and a unique perspective on approaches to move research from bench to bedside. For more information, click here

Program Faculty

  • Ambati, Jayakrishna

    Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness

  • Arandjelovic, Sanja

    Innate immunity, Cell clearance, Inflammatory and autoimmune disease

  • Barker, Thomas H.

    Matrix Biology and Engineering

  • Bauer, Todd

    Cancer metastasis, chemotherapy resistance, genetic and epigenetic regulation

  • Bloom, George S.

    Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders

  • Brown, Michael G.

    Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

  • Bullock, Timothy N.

    Pathways to enhance T cell function in tumors.

  • Cai, Chuanxi

    Molecular Physiology and Biological Physics

  • Caliari, Steven

    Engineering biomaterials as cellular microenvironments

  • Cheng, Lily S

    Surgery

  • Christ, George

    Functional Genomics

  • Civelek, Mete

    Systems Genetics Approaches to Understand Cardiometabolic Traits

  • Cross, Janet V.

    Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention

  • Farber, Charles R.

    Systems Genetics of Skeletal Development and Maintenance

  • Felder, Robin A.

    Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.

  • Ferris, Heather

    Brain metabolism, cognitive decline, insulin signaling and Alzheimer's disease

  • Flowers, Sarah

    Impact of APOE and lipid metabolism on cell function in Alzheimer's disease.

  • Gaultier, Alban

    Exploring new therapeutics avenues to treat Multiple Sclerosis.

  • Gelfand, Bradley

    Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.

  • Gioeli, Daniel

    Signal transduction in cancer cells

  • Goldfarb, Adam N.

    Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis

  • Janes, Kevin A.

    Systems-biology approaches to cancer biology and virology.

  • Landen, Charles

    Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies

  • Lazzara, Matthew

    Cellular Engineering

  • Le, Lu Q

    Cancer Biology, Tumor Cell of Origin and Tumor Microenvironment, Neurofibromatosis and Schwann Cell Biology, Skin and Hair Stem Cell Biology & Regeneration

  • Li, Hui

    Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

  • Loughran, Jr., Thomas P

    Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)

  • Luckey, Chance John

    Immune Memory

  • Ma, Jianjie

    Physiology & Biophysics

  • Mahadevan, Mani S.

    Molecular Mechanisms of Myotonic Muscular Dystrophy

  • Mauldin, Ileana Soto

    Pathology

  • McNamara, Coleen A.

    Immune System Regulation of Cardiometabolic Disease

  • Miller, Clint L.

    Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

  • Mohi, Golam

    Cell signaling, stem cell biology, molecular and epigenetic mechanisms of blood and breast cancers

  • Moskaluk, Christopher A.

    Molecular pathogenesis and genomic analysis of human cancers

  • Naegle, Kristen

    Regulation and function of tyrosine phosphorylation in complex networks

  • Owens, Gary K.

    Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke

  • Papin, Jason A.

    Systems biology, infectious disease, cancer, toxicology, metabolic engineering

  • Paschal, Bryce M.

    Nuclear Transport, Signaling, and Cancer

  • Peirce-Cottler, Shayn M.

    Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

  • Petri, William A.

    Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections

  • Purow, Benjamin W.

    Novel therapeutic approaches to brain cancers and to other neurologic diseases

  • Sheybani, Natasha

    Biomedical Engineering

  • Sontheimer, Harald

    Role of Glia in Neurological Illnesses and Cancer

  • Syed, Sana

    Understanding why a subset of children living in in low- and middle-income countries around the world develop growth and vaccine failure. Investigating the causes and progression of inflammatory enteropathies of the gastrointestinal lumen. Integrating data science-driven approaches with medicine to drive precision medicine.

  • Tao, Jianguo

    Pathology

  • Trinh, Bon Q

    Understanding Protein and RNA regulations of gene expression via chromatin structure in myeloid cell development and diseases

  • Vande Pol, Scott B.

    How Viruses, Particularly Papillomaviruses, Can Cause Cancer

  • Venton, B. Jill

    Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

  • Witt, Russell Gardner

    Unraveling the Role of Obesity, Diet, and Lifestyle Factors in Melanoma Progression and Treatment Efficacy

  • Yates, Paul A.

    Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.

  • Zimring, James C

    Alloimmunity in Transfusion and Transplantation , Oxidant Stress Biology in Health and Disease