Research in Infectious Diseases at UVA provides rich interdisciplinary experiences in the molecular biology, immunology, cell biology, and pathogenesis of infectious diseases as well as vaccine development, therapeutics and diagnostic technologies for infectious agents. Trainees have opportunities to conduct research with over 30 different mentors from eight different departments
The Infectious Diseases (ID) Training Program is currently in its 5th decade of consecutive NIH funding. This program brings together an internationally recognized clinical program in infectious diseases and international health and superb basic molecular and cellular biologists. The core philosophy of the program is that interactions between basic scientists and clinicians in training and research will spark innovative approaches to diagnose, treat and prevent infections
A basic philosophy of the program is that through interactions of basic scientists and clinicians in research and training, will come the breakthrough science that leads to new interventions to diagnose, treat and prevent infections.
The Infectious Diseases Training Program features side-by-side education of predoctoral students, M.D.s, and Ph.D. postdoctoral fellows. Training is enriched by research-in-progress sessions, seminar series, and journal clubs that integrate both clinical and basic research aspects of infectious diseases.
The Global Biothreats Training Program focuses on the ways that key infectious agents of worldwide notoriety cause disease. Resources for this program include a well-equipped Biosafety Level 3 facility for trained and approved users. The Global Biothreats Training Program features coursework and lectures that highlight not only mechanisms of pathogenesis, but also the regulatory, policy, and societal impacts of global biothreats.
Genetic approaches, cellular and molecular biology of intracellular pathogen infection
Braciale, Thomas J.
T Lymphocyte Responses To Virus Infection
Brown, Michael G.
Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
Bullock, Timothy N.
Pathways to enhance T cell function in tumors.
Casanova, James E.
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.
Chalfant, Charles Edward
Hematology and Oncology, Cell Biology, Lipid Signaling, Cancer Cell Signaling, and RNA Biology
Herpes Simplex Virus Infection of Neurons
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Cowardin, Carrie A.
The maternal and infant microbiome in childhood growth and immunity
Criss, Alison K.
Cellular and molecular mechanisms of Neisserial pathogenesis
Host/pathogen Interaction - Chlamydia Infection
Egelman, Edward H.
Structure and Function of Macromolecular Complexes Using Electron Microscopy
Engel, Daniel A.
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika
Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, proteomics
Ford, Roseanne M.
Bacterial attachment and biofilms, microbial transport in porous media
Super-resolution fluorescence imaging of bacterial cells
Garcia-Blanco, Mariano A.
RNA-protein interactions in antiviral immunity and autoimmune diseases.
Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum
Hahn, Young S.
Immune regulation for HCV infection and chronic liver inflammation
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Harris, Tajie H.
Immune response to infectious disease in the CNS
Janes, Kevin A.
Systems-biology approaches to cancer biology and virology.
Kasson, Peter M.
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.
Kedes, Dean H.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Kendall, Melissa M.
Bacterial cell signaling, host-pathogen interactions, intestinal pathogens
Wnt/PCP signaling in inner ear development Mouse models for human deafness Wnt/PCP signaling in neural tube closure
Lukens, John R.
Understanding How Immunological Pathways Contribute to Neurodegenerative, Neurodevelopmental, Mental and Behavior Disorders
Mann, Barbara J.
SARS CoV-2 Vaccines and Therapeutics; Pathogenicity of Francisella tularensis and vaccines
Papin, Jason A.
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
Petri, William A.
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Structure and assembly of HIV, virus/host interactions, structural biology of the innate immune system
Rekosh, David M.
Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation
Viral immunology, T cells, Macrophages, Tissue repair
Molecular and bioelectric devices; tissue regeneration.
Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Woodfolk, Judith A.
The immune response to common cold and allergens in health and disease.
Zeichner, Steven L.
Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.