Biotechnology
About
Research in Biotechnology at UVA brings together researchers from all biomedical, engineering, and chemical sciences at UVA to promote state-of-the-art collaborative science. From this innovative science comes conceptual breakthroughs and new products.In 2000, we established a Biotechnology Training Program (BTP) at UVA with the goal of providing fertile ground for the development of future leaders in science and technology. It is one of only 19 BTPs nationwide. Our graduates are scientific leaders at major biotechnology companies, federal agencies, and foundations, and lead independent research labs at universities, or are postdoctoral scientists at institutions nationwide.
The BTP offers many enhancements. The 2 – 3 month company externship training is transformative. Some students alter career plans towards academia or industrial research. Others affirm prior career directions or receive unexpected offers of employment. All make important contributions, some publish articles, and invariably the collaboration enhances thesis projects. Venues are worldwide, from Boston to San Francisco to Australia, England, Holland, Finland, Germany, Spain and Sweden.
We also offer company tours – including Merck, Pfizer, BD; panel discussions with industrial leaders – including BTP alumni; as well as seminars and biannual symposia that gather recognized innovators under the umbrella of a broad scientific theme.
Our outstanding mentors from across the sciences at UVA are award-winning leaders in their fields, with success in nurturing the best from our students. Many hold patents, and several have started companies. This is an exciting time for our students to be at the frontlines of science and technology.
Faculty
Ai, Huiwang
Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Bochkis, Irina
Epigenetic and genetic mechanisms underlying metabolic disease
Braciale, Thomas J.
T Lymphocyte Responses To Virus Infection
Brown, Michael G.
Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
Caliari, Steven
Engineering biomaterials as cellular microenvironments
Columbus, Linda
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Deppmann, Christopher
Elucidating and Understanding the Mechanisms Underlying Nervous System Development
Derewenda, Zygmunt S.
Structure-function relationships in proteins
DeSimone, Douglas W.
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
Dolatshahi, Sepideh
Systems Immunology, Cancer Systems Biology, , Neonatal and Maternal Immunology
Engel, Daniel A.
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika
Engelhard, Victor H.
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity
Ewald, Sarah
Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, proteomics
Fallahi-Sichani, Mohammad
Cancer systems biology, Single-cell quantitative biology, Computational modeling
Ford, Roseanne M.
Bacterial attachment and biofilms, microbial transport in porous media
Fox, Jay W.
Basement Membrane Structure and Metalloproteinases
Gahlmann, Andreas
Super-resolution fluorescence imaging of bacterial cells
Gaultier, Alban
Exploring new therapeutics avenues to treat Multiple Sclerosis.
Guler, Jennifer
Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum
Hahn, Young S.
Immune regulation for HCV infection and chronic liver inflammation
Hammarskjöld, Marie-Louise
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Harris, Tajie H.
Immune response to infectious disease in the CNS
Harris, Thurl E
Molecular mechanisms controlling insulin signaling and fat synthesis.
Holmes, Jeffrey W.
Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
Hsu, Ku-Lung
Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry
Hunt, Donald F.
Analytical Biochemistry
Isakson, Brant
Translating our discoveries in the microcirculation to tangible benefits in patients.
Janes, Kevin A.
Systems-biology approaches to cancer biology and virology.
Kedes, Dean H.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Kelly, Kimberly
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
Kundu, Bijoy
Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy
Lampe, Kyle
Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive microenvironments
Landers, James P.
Bioanalytical Chemistry on Microchips
Laurie, Gordon W.
Restoration of Homeostasis in Disease
Lee, Kevin S.
Neuronal Vulnerability: A Study of Cellular Mechanism
Li, Hui
Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
Lu, Xiaowei
Wnt/PCP signaling in inner ear development Mouse models for human deafness Wnt/PCP signaling in neural tube closure
Lynch, Kevin R.
Chemical biology of sphingosine 1-phosphate
Mann, Barbara J.
SARS CoV-2 Vaccines and Therapeutics; Pathogenicity of Francisella tularensis and vaccines
McNamara, Coleen A.
Immune System Regulation of Cardiometabolic Disease
Moskaluk, Christopher A.
Molecular pathogenesis and genomic analysis of human cancers
Naegle, Kristen
Regulation and function of tyrosine phosphorylation in complex networks
Papin, Jason A.
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
Pearson, William R.
Protein Evolution; Computational Biology
Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Petri, William A.
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Pompano, Rebecca
Bioanalytical tools for inflammatory disease
Pornillos, Owen
Structure and assembly of HIV, virus/host interactions, structural biology of the innate immune system
Purow, Benjamin W.
Novel therapeutic approaches to brain cancers and to other neurologic diseases
Rekosh, David M.
Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation
Saucerman, Jeffrey J.
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Sheynkman, Gloria M.
Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease
Shin, Jung-Bum
Auditory Neurobiology
Swami, Nathan
Molecular and bioelectric devices; tissue regeneration.
Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
Wang, Bowen
Toward better understanding of and innovative therapies for peripheral vascular diseases
Yates, Paul A.
Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.
Yeager, Mark
Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
Zang, Chongzhi
Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Advanced machine learning; Theoretical and computational biophysic
Zhang, Tian
Biochemistry
Zhu, J. Julius
Neural Circuits in Healthy and Diseased Brains
Zong, Hui
Early detection, cancer prevention, and tumor microenvironment
Zunder, Eli
Single Cell Analysis