Biotechnology

students at biotech seminarResearch in Biotechnology at UVA brings together researchers from all biomedical, engineering, and chemical sciences at UVA to promote state-of-the-art collaborative science.  From this innovative science comes conceptual breakthroughs and new products.In 2000, we established a Biotechnology Training Program (BTP) at UVA with the goal of providing fertile ground for the development of future leaders in science and technology.  It is one of only 19 BTPs nationwide.  Our graduates are scientific leaders at major biotechnology companies, federal agencies, and foundations, and lead independent research labs at universities, or are postdoctoral scientists at institutions nationwide.

The BTP offers many enhancements.  The 2 – 3 month company externship training is transformative.  Some students alter career plans towards academia or industrial research.  Others affirm prior career directions or receive unexpected offers of employment.  All make important contributions, some publish articles, and invariably the collaboration enhances thesis projects.  Venues are worldwide, from Boston to San Francisco to Australia, England, Holland, Finland, Germany, Spain and Sweden.

We also offer company tours – including Merck, Pfizer, BD;  panel discussions with industrial leaders – including BTP alumni; as well as seminars and biannual symposia that gather recognized innovators under the umbrella of a broad scientific theme.

Our outstanding mentors from across the sciences at UVA are award-winning leaders in their fields, with success in nurturing the best from our students.  Many hold patents, and several have started companies.  This is an exciting time for our students to be at the frontlines of science and technology.

Faculty
  • Adli, Mazhar

    Identify and target key genomic and epigenomic drivers in cancer

  • Ai, Huiwang

    Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

  • Bochkis, Irina

    Epigenetic and genetic mechanisms underlying metabolic disease

  • Braciale, Thomas J.

    T Lymphocyte Responses To Virus Infection

  • Brown, Michael G.

    Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

  • Caliari, Steven

    Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment

  • Columbus, Linda

    Biophysical Chemistry: Membrane protein structure, function, and dynamics

  • Corwin, Jeffrey T.

    Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.

  • Deppmann, Christopher

    Elucidating and Understanding the Mechanisms Underlying Nervous System Development

  • Derewenda, Zygmunt S.

    Structure-function relationships in proteins

  • DeSimone, Douglas W.

    Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

  • Dutta, Anindya

    Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer

  • Engel, Daniel A.

    Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.

  • Engelhard, Victor H.

    Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Tertiary lymphoid structures and intratumoral immunity

  • Ewald, Sarah

    Innate immunity, chronic disease, host-parasite interactions

  • Ford, Roseanne M.

    Bacterial attachment and biofilms, microbial transport in porous media

  • Fox, Jay W.

    Basement Membrane Structure and Metalloproteinases

  • Gahlmann, Andreas

    Super-resolution fluorescence imaging of bacterial cells

  • Ganser-Pornillos, Barbie

    The Structural Biology of HIV assembly

  • Gaultier, Alban

    Exploring new therapeutics avenues to treat Multiple Sclerosis.

  • Guler, Jennifer

    Cell Biology and Parasitology.

  • Hahn, Young S.

    Immune regulation for HCV infection and chronic liver inflammation

  • Hammarskjöld, Marie-Louise

    Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses

  • Harris, Tajie H.

    Immune response to infectious disease in the CNS

  • Holmes, Jeffrey W.

    Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.

  • Hsu, Ku-Lung

    Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry

  • Hunt, Donald F.

    Analytical Biochemistry

  • Isakson, Brant

    Translating our discoveries in the microcirculation to tangible benefits in patients.

  • Janes, Kevin A.

    Systems-biology approaches to cancer biology and virology.

  • Kedes, Dean H.

    Human Herpes virus associated with malignancy, including Kaposi’s Sarcoma

  • Kelly, Kimberly

    Advancement in the design of imaging agents; molecular imaging and radiological sciences.

  • Kester, Mark

    Nanotechnologies for targeted drug delivery

  • Kipnis, Jonathan

    Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration

  • Kundu, Bijoy

    Positron Emission Tomography Imaging of Remodeling of Myocardial Glucose Metabolism in Pressure Overload Left Ventricular Hypertrophy

  • Lampe, Kyle

    Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive microenvironments

  • Landers, James P.

    Bioanalytical Chemistry on Microchips

  • Laurie, Gordon W.

    Role of Prosecretory Mitogen ‘Lacritin’ in Epithelial Homeostasis, Secretion and Innate Defense

  • Lawrence, Michael B.

    Vascular and Molecular Engineering

  • Lee, Kevin S.

    Neuronal Vulnerability: A Study of Cellular Mechanism

  • Li, Hui

    Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

  • Lu, Xiaowei

    Developmental regulation of planar cell polarity in the mammalian nervous
    system

  • Lynch, Kevin R.

    Chemical biology of sphingosine 1-phosphate

  • Mann, Barbara J.

    Pathogenicity of Francisella tularensis and vaccines

  • McConnell, Michael J

    The Cause and Consequence of Somatic Mosaicism in Neurons

  • McNamara, Coleen A.

    Atherosclerosis, Obesity, Diabetes

  • Moskaluk, Christopher A.

    Molecular pathogenesis and genomic analysis of human cancers

  • Naegle, Kristen

    Regulation and function of tyrosine phosphorylation in complex networks

  • Papin, Jason A.

    Systems biology, infectious disease, cancer, toxicology, metabolic engineering

  • Pearson, William R.

    Protein Evolution; Computational Biology

  • Peirce-Cottler, Shayn M.

    Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

  • Petri, William A.

    Immune mechanisms of defense against enteric (diarrheal) infections

  • Pompano, Rebecca

    Bioanalytical tools for inflammatory disease

  • Pornillos, Owen

    Structure and assembly of HIV Virus/host interactions; Structural biology of the innate immune system

  • Purow, Benjamin W.

    Novel therapeutic approaches to brain cancers and to other neurologic diseases

  • Rekosh, David M.

    Human Immunodeficiency; Virus Gene Expression

  • Rich, Stephen S.

    Genetic basis of common human disease, including type 1 diabetes, diabetic complications, ischemic stroke, atherosclerosis

  • Saucerman, Jeffrey J.

    Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

  • Shin, Jung-Bum

    Auditory Neurobiology

  • Swami, Nathan

    Molecular and bioelectric devices; tissue regeneration.

  • Venton, B. Jill

    Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents

  • Yates, Paul A.

    Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.

  • Yeager, Mark

    Cardiac Gap Junction Membrane Channels / IntegrinsWater Channels / Rotavirus / Reovirus / Retrovirus

  • Zang, Chongzhi

    Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Theoretical and computational biophysics

  • Zhu, J. Julius

    Neural Circuits in Healthy and Diseased Brains

  • Zong, Hui

    Early detection, cancer prevention, and tumor microenvironment

  • Zunder, Eli

    Stem Cell Behavior