Research in Neuroscience at UVA explores basic questions about the workings of the brain, the neural bases for mental disorders, neurodegeneration, and other common brain dysfunction.Sensory systems, behavior, neurodegeneration and memory loss, addiction and motor systems are just a few examples of areas within neuroscience that are current topics of study in our program. It is an exciting time to be a neuroscientist. New advanced techniques allow for macro (fMRI, Optigenetics) and micro (capillary electrophoresis, electrophysiology) analysis of neuronal systems. The Neuroscience Graduate Program at the University of Virginia is training experimentalists in basic science and translational research, always with an eye on disease relevance. As such, we stress didactic learning for the first year and experiential laboratory-based learning in the second year and beyond.
Our diverse and interdepartmental faculty allows for dynamic, cross-disciplinary training in a variety of basic and translational neuroscience research areas that include the following: Building and Wiring the Brain; Sensory systems; Neurodegeneration and Brain Injury; Behavior and Epigenetics; Glial and Immune Cells in Health and Disease; Neurodevelopment, Neurocognitive and Neuropsychiatric Disorders; and the Neurobiology of Ion Channels.
- Ai, Huiwang
Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
- Beenhakker, Mark P.
Circuit mechanisms of sleep and epilepsy
- Campbell, John
The Neurobiology of Energy Balance
- Coan, James A.
Neuroscience of Emotional Expression and Individual Emotion-Regulation Capabilities
- Creutz, Carl E.
Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis
- Dwyer, Noelle
Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
- Eyo, Ukpong Bassey
- Gaultier, Alban
Exploring new therapeutics avenues to treat Multiple Sclerosis.
- Hill, David
Development and plasticity of sensory systems
- Keller, Raymond E.
Cellular and molecular mechanisms of morphogenesis
- Kucenas, Sarah C.
The role of glia in the development, maintenance and regeneration of the nervous system
- Legon, Wynn
- Lu, Xiaowei
Developmental regulation of planar cell polarity in the mammalian nervous system
- Mahadevan, Mani S.
Molecular Mechanisms of Myotonic Muscular Dystrophy
- Morris, James P.
Social perception and cognition; Social Neuroscience; Human Neuroscience
- Perez-Reyes, Edward
Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.
- Provencio, Ignacio
The Role of Melanopsin Retinal Ganglion Cells in the Photic Regulation of Mammalian Circadian Rhythms
- Ravichandran, Kodi S.
Apoptotic cell clearance mechanisms in health and disease
- Siegrist, Sarah
Regulation of neural stem cell proliferation during development and adulthood
- Thisse, Christine I.
Molecular Mechanisms of Early Vertebrate Development and Morphogenesis. Application to Stem Cell Biology and Regenerative Medicine
- Williams, Cedric L.
Studies of various aspects of learning, memory, olfactory discrimination and explosive detection. We develop computer driven learning programs that produce optimal olfactory discrimination and detection learning in rodents.
- Zeitlin, Scott O.
Mechanisms of Huntington’s Disease Pathogenesis
- Zunder, Eli
Stem Cell Behavior
- Ambati, Jayakrishna
Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness
- Bloom, George S.
Pathogenic mechanisms in Alzheimer’s Disease and other neurodegenerative disorders
- Cang, Jianhua
Mouse Visual System, physiology, functional imaging, genetics, molecular, behavioral, and computational methods
- Condron, Barry G.
Regulation and Function Serotonergic Neurons During Development
- Deppmann, Christopher
Elucidating and Understanding the Mechanisms Underlying Nervous System Development
- Erisir, Alev
Developmental Plasticity and Neuropathology of Synaptic Circuitries.
- Ferris, Heather
The Role of Diabetes in Cognitive Decline
- Goodkin, Howard P.
- Grossman, Tobias
Brain processes that underpin social interaction and cognition during infancy
- Halme, Adrian J.
Regeneration and Systemic Responses to Tissue Damage
- Hirsh, Jay
Molecular genetics; development and function of neurotransmitter-synthesizing neurons in Drosophila
- Kapur, Jaideep
Pathophysiology of Status Epilepticus; Mechanisms and pathways of seizure spread
- Lampe, Kyle
Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive microenvironments
- Liu, Xiaorong
Developing novel neuroprotection strategies to preserve vision in glaucoma
- Lukens, John R.
Understanding How Immunological Pathways Contribute to Neurodegenerative, Neurodevelopmental, Mental and Behavior Disorders
- Meliza, C. Daniel
Neural Mechanisms of Pattern Learning and Recognition in the Auditory System
- Parichy, David
Developmental Genetics, Evolution and Regeneration of Adult Morphology in Vertebrates
- Price, Richard J.
Image Guided Drug and Gene Delivery for Neurodegeneration and Cancer; Focused Ultrasound and Immunotherapy; Arteriogenesis and Angiogenesis
- Provencio, Javier
Innate Inflammatory Pathways Associated with Acute Aneurysmal Subarachnoid Hemorrhage
- Scott, Michael M.
Investigation of the neuronal circuits and epigenetic modifications involved in the control of food intake, impulsivity and novelty seeking behavior
- Tvrdik, Petr
- Winckler, Bettina
Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.
- Zhu, J. Julius
Neural Circuits in Healthy and Diseased Brains
- Bayliss, Douglas A.
Mechanisms of neuromodulation in central neurons
- Brunjes, Peter C.
Use the olfactory system to examine general problems in the brain maturation, including the role of afferent activity on tissue development and the interplay between evolution and development.
- Cliffe, Anna
Herpes Simplex Virus Infection of Neurons
- Connelly, Jessica J.
Epigenetic mechanisms involved in complex human disease
- Druzgal, Thomas Jason
Multi-modal brain MRI to study different aspects of neurodegenerative diseases. Effects of mild traumatic brain injury on student athletes. Parkinson’s Disease and essential tremor.
- Ewald, Sarah
Innate immunity, chronic disease, host-parasite interactions
- Grainger, Robert M.
Molecular embryology–gene regulation in cells committed to specific developmental lineages
- Guler, Ali D.
Signal Processing by the Central Nervous System
- Harris, Tajie H.
Immune response to infectious disease in the CNS
- Kawasaki, Masashi
Neuroethology of electric fish
- Kuan, Alex
- Lee, Kevin S.
Neuronal Vulnerability: A Study of Cellular Mechanism
- Long, Nicole
Neural mechanisms of human memory
- Lynch, Wendy J.
Behavioral Pharmacology, Sex Differences, Animal Models of Addiction
- Patel, Manoj
Modulation of sodium channel gating by beta subunits and novel sodium channel blockers; Synaptic transmission in dorsal horn neurons
- Purow, Benjamin W.
Novel therapeutic approaches to brain cancers and to other neurologic diseases
- Shin, Jung-Bum
- Stone, James
Traumatic Brain Injury
- Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
- Yates, Paul A.
Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.
- Zong, Hui
Early detection, cancer prevention, and tumor microenvironment