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Microbiology

About

Research in Microbiology Research in Microbiology at UVA spans the fundamental molecular processes of viruses, bacteria, fungi, and parasites of major importance to human health.Many fundamental biological processes have been uncovered through the study of bacteria, viruses and eukaryotic unicellular microorganisms, and these studies have also revealed mechanisms by which infectious agents cause disease. Our students and faculty examine how microbes replicate, invade the host cell, colonize the host and interact with the immune system.  To this end we use state-of-the-art experimental approaches drawn from the fields of molecular biology, biochemistry, genetics, structural biology, cell biology, physiology, cellular and sub-cellular imaging, genomics and bioinformatics.

The microbiology research community at UVA spans multiple basic science and clinical departments.  It features numerous laboratories that are engaged in highly interactive and collaborative research, with many researchers sharing authorship on high-profile publications.  Our research findings provide insights into basic biology and also provide foundations for translational applications, such as vaccine development and new therapeutic approaches for treating infections.

The robust educational opportunities available include specialized coursework, laboratory rotations, journal clubs, and weekly seminars highlighting the work of trainees as well as that of internationally renowned scientists.

Training in Microbiology at UVA equips our graduates to pursue diverse career options, including postdoctoral positions in academia, as well as jobs in government, the pharmaceutical and biotechnology industries, collegiate teaching, public policy, consulting and patent law.

Faculty

  • Ambati, Jayakrishna

    Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness

  • Cafiso, David S.

    Molecular Mechanisms for Membrane Transport and Cell Signaling

  • Casanova, James E.

    Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
    Cell Biology of bacterial pathogenesis.
    The innate immune response to bacterial infection.

  • Cliffe, Anna

    Herpes Simplex Virus Infection of Neurons

  • Columbus, Linda

    Biophysical Chemistry: Membrane protein structure, function, and dynamics

  • Cowardin, Carrie A.

    The maternal and infant microbiome in childhood growth and immunity

  • Criss, Alison K.

    Cellular and molecular mechanisms of Neisserial pathogenesis

  • Derré, Isabelle

    Host/pathogen Interaction - Chlamydia Infection

  • Egelman, Edward H.

    Structure and Function of Macromolecular Complexes Using Electron Microscopy

  • Elliott, Michael R.

    Macrophage effector functions in inflammation and immunotherapy

  • Engel, Daniel A.

    Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika

  • Ewald, Sarah

    Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, proteomics

  • Ford, Roseanne M.

    Bacterial attachment and biofilms, microbial transport in porous media

  • Gahlmann, Andreas

    Super-resolution fluorescence imaging of bacterial cells

  • Gaultier, Alban

    Exploring new therapeutics avenues to treat Multiple Sclerosis.

  • Guler, Jennifer

    Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum

  • Hahn, Young S.

    Immune regulation for HCV infection and chronic liver inflammation

  • Harris, Tajie H.

    Immune response to infectious disease in the CNS

  • Hughes, Molly A.

    Biodefense and emerging pathogens

  • Janes, Kevin A.

    Systems-biology approaches to cancer biology and virology.

  • Kendall, Melissa M.

    Bacterial cell signaling, host-pathogen interactions, intestinal pathogens

  • Kozminski, Keith G.

    Regulation of Polarized Morphogenesis

  • Mauldin, Ileana Soto

    Pathology

  • Papin, Jason A.

    Systems biology, infectious disease, cancer, toxicology, metabolic engineering

  • Petri, William A.

    Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections

  • Pompano, Rebecca

    Bioanalytical tools for inflammatory disease

  • Ramakrishnan, Girija

    Microbial Pathogenesis

  • Rekosh, David M.

    Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation

  • Rutkowski, Melanie

    Influence of commensal microbes on immune homeostasis, anti-tumor immunity, and metastasis

  • Wang, Qiwei

    Cancer biology and immunology, Immuno-oncology, Immunometabolism, Genetically-engineered mouse models

  • Zegarra-Ruiz, Daniel Fernando

    Unraveling the role of host microbe interactions in autoimmune diseases

  • Zeichner, Steven L.

    Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.