Biophysics
About
The Biophysics Program is an interdisciplinary degree-granting program that has faculty in 13 departments over three schools or colleges across the Grounds of the University of Virginia. The faculty and their trainees conduct research in a wide range of areas relevant to basic biological phenomena as well as human health, while sharing common ground in the use of quantitative approaches that emphasize chemistry, computation, mathematics and physics.
Program Faculty
Ai, Huiwang
Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Bao, Huan
Biophysics of membrane pore formation; research and therapeutic applications of lipid nanoparticles.
Bekiranov, Stefan
Computational Biology; Bioinformatics; Precision Medicine; Machine Learning/AI; Quantum Computing
Bourne, Philip E
Data Science
Bushweller, John H.
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
Cafiso, David S.
Molecular Mechanisms for Membrane Transport and Cell Signaling
Columbus, Linda
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Derewenda, Zygmunt S.
Structure-function relationships in proteins
DuBay, Kateri
The design of self-assembling nanomaterials
Ebrahim, Seham
Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging
Egelman, Edward H.
Structure and Function of Macromolecular Complexes Using Electron Microscopy
Ford, Roseanne M.
Bacterial attachment and biofilms, microbial transport in porous media
Gahlmann, Andreas
Super-resolution fluorescence imaging of bacterial cells
Guler, Jennifer
Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum
Hunt, Donald F.
Analytical Biochemistry
Isakson, Brant
Translating our discoveries in the microcirculation to tangible benefits in patients.
Jomaa, Ahmad
Localisation of nascent proteins to sub-cellular compartments
Kasson, Peter M.
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.
Kelly, Kimberly
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
Kenworthy, Anne
Architecture and function of biological membranes
Landers, James P.
Bioanalytical Chemistry on Microchips
Levental, Ilya
Composition, Biophysics and Physiology of Cellular Membranes
Minor, Wladek
Structure-Function Relationships in Macromolecules; Infectious Diseases and Drug Discovery; Bioinformatics and Big Data; Scientific Reproducibility
Papin, Jason A.
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Qi, Ling
Delineate the physiological importance and structure-function relationship of ER-associated degradation in humans.
Redemann, Stefanie
Chromosome segregation and aneuploidy in meiosis and mitosis
Saucerman, Jeffrey J.
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Sheynkman, Gloria M.
Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease
Somlyo, Avril V.
Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.
Sonkusare, Swapnil
Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders
Stukenberg, P. Todd
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Swami, Nathan
Molecular and bioelectric devices; tissue regeneration.
Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
Xie, Jinghang
Molecular Imaging; Cancer Immunology; Vaccines; Antibiotic Resistance.
Zimmer, Jochen
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.