Experimental Pathology
The Molecular and Cellular Basis of Disease (MCBD) graduate program confers the PhD in Experimental Pathology. The program is designed for students with a research interest in the mechanisms of human disease processes, with a particular emphasis on the skills necessary to perform translational research. In addition to basic laboratory skills, the program offers the opportunity for collaborative work with top-ranked and internationally recognized pathologists and other clinicians as part of PhD training. These experiences provide our trainees with an understanding of modern medical problems and a unique perspective on approaches to move research from bench to bedside.
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Program Faculty
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Ambati, Jayakrishna
Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness
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Barker, Thomas H.
Matrix Biology and Engineering
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Bloom, George S.
Pathogenic mechanisms in Alzheimer’s Disease and other neurodegenerative disorders
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Braciale, Thomas J.
T Lymphocyte Responses To Virus Infection
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Brown, Michael G.
Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
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Bullock, Timothy N.
Pathways to enhance T cell function in tumors.
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Caliari, Steven
Engineering dynamic biomaterials to explore the interplay between cells and their microenvironment
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Christ, George
Functional Genomics
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Civelek, Mete
Systems Genetics Approaches to Understand Cardiometabolic Traits
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Cross, Janet V.
Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention
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Dutta, Anindya
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
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Felder, Robin A.
Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.
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Ferris, Heather
The Role of Diabetes in Cognitive Decline
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Gaultier, Alban
Exploring new therapeutics avenues to treat Multiple Sclerosis.
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Gelfand, Bradley
Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.
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Gioeli, Daniel
Signal transduction in cancer cells
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Goldfarb, Adam N.
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
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Janes, Kevin A.
Systems-biology approaches to cancer biology and virology.
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Kester, Mark
Nanotechnologies for targeted drug delivery
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Landen, Charles
Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies
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Lazzara, Matthew
Cellular Engineering
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Li, Hui
Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
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Loughran, Jr., Thomas P
Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)
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Luckey, Chance John
Immune Memory
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Mahadevan, Mani S.
Molecular Mechanisms of Myotonic Muscular Dystrophy
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McNamara, Coleen A.
Atherosclerosis, Obesity, Diabetes
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Miller, Clint
Assistant Professor, Public Health Sciences
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Mohi, Golam
Cell signaling, hematopoietic stem cell biology, molecular and epigenetic mechanisms of leukemia.
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Moore, Sean
Structure and Function of the GI Tract in the Context of Childhood Nutrition, Growth, Immunity, and Host-microbe Interactions
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Moskaluk, Christopher A.
Molecular pathogenesis and genomic analysis of human cancers
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Naegle, Kristen
Regulation and function of tyrosine phosphorylation in complex networks
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Owens, Gary K.
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke
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Papin, Jason A.
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
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Paschal, Bryce M.
Nuclear Transport, Signaling, and Cancer
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Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
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Petri, William A.
Immune mechanisms of defense against enteric (diarrheal) infections
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Purow, Benjamin W.
Novel therapeutic approaches to brain cancers and to other neurologic diseases
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Tung, Kenneth S.
Mechanisms of Tolerance and Autoimmunity to Gonad-Specific Antigens
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Vande Pol, Scott B.
How Viruses, Particularly Papillomaviruses, Can Cause Cancer
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Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
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Yates, Paul A.
Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.