Experimental Pathology
About
The Molecular and Cellular Basis of Disease (MCBD) graduate program confers the PhD in Experimental Pathology. The program is designed for students with a research interest in the mechanisms of human disease processes, with a particular emphasis on the skills necessary to perform translational research. In addition to basic laboratory skills, the program offers the opportunity for collaborative work with top-ranked and internationally recognized pathologists and other clinicians as part of PhD training. These experiences provide our trainees with an understanding of modern medical problems and a unique perspective on approaches to move research from bench to bedside. For more information, click here…
Program Faculty
Ambati, Jayakrishna
Understanding the Molecular Basis of Macular Degeneration in Order to Hasten the Eradication of Blindness
Arandjelovic, Sanja
Innate immunity, Cell clearance, Inflammatory and autoimmune disease
Barker, Thomas H.
Matrix Biology and Engineering
Bauer, Todd
Cancer metastasis, chemotherapy resistance, genetic and epigenetic regulation
Bloom, George S.
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
Brown, Michael G.
Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation
Bullock, Timothy N.
Pathways to enhance T cell function in tumors.
Cai, Chuanxi
Molecular Physiology and Biological Physics
Caliari, Steven
Engineering biomaterials as cellular microenvironments
Cheng, Lily S
Surgery
Christ, George
Functional Genomics
Civelek, Mete
Systems Genetics Approaches to Understand Cardiometabolic Traits
Cross, Janet V.
Contribution of the Inflammatory Microenvironment to Tumor Initiation, Progression and Metastasis; Molecular Mechanisms of Cancer Chemoprevention
Farber, Charles R.
Systems Genetics of Skeletal Development and Maintenance
Felder, Robin A.
Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.
Ferris, Heather
Brain metabolism, cognitive decline, insulin signaling and Alzheimer's disease
Flowers, Sarah
Impact of APOE and lipid metabolism on cell function in Alzheimer's disease.
Gaultier, Alban
Exploring new therapeutics avenues to treat Multiple Sclerosis.
Gelfand, Bradley
Blinding disease age-related macular degeneration, utilizing the tools of immunology, molecular biology, and engineering.
Gioeli, Daniel
Signal transduction in cancer cells
Goldfarb, Adam N.
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Janes, Kevin A.
Systems-biology approaches to cancer biology and virology.
Landen, Charles
Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies
Lazzara, Matthew
Cellular Engineering
Le, Lu Q
Cancer Biology, Tumor Cell of Origin and Tumor Microenvironment, Neurofibromatosis and Schwann Cell Biology, Skin and Hair Stem Cell Biology & Regeneration
Li, Hui
Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development
Loughran, Jr., Thomas P
Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)
Luckey, Chance John
Immune Memory
Ma, Jianjie
Physiology & Biophysics
Mahadevan, Mani S.
Molecular Mechanisms of Myotonic Muscular Dystrophy
Mauldin, Ileana Soto
Pathology
McNamara, Coleen A.
Immune System Regulation of Cardiometabolic Disease
Miller, Clint L.
Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology
Mohi, Golam
Cell signaling, stem cell biology, molecular and epigenetic mechanisms of blood and breast cancers
Moskaluk, Christopher A.
Molecular pathogenesis and genomic analysis of human cancers
Naegle, Kristen
Regulation and function of tyrosine phosphorylation in complex networks
Owens, Gary K.
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or Stroke
Papin, Jason A.
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
Paschal, Bryce M.
Nuclear Transport, Signaling, and Cancer
Peirce-Cottler, Shayn M.
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Petri, William A.
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Purow, Benjamin W.
Novel therapeutic approaches to brain cancers and to other neurologic diseases
Sheybani, Natasha
Biomedical Engineering
Sontheimer, Harald
Role of Glia in Neurological Illnesses and Cancer
Tao, Jianguo
Pathology
Trinh, Bon Q
Understanding Protein and RNA regulations of gene expression via chromatin structure in myeloid cell development and diseases
Vande Pol, Scott B.
How Viruses, Particularly Papillomaviruses, Can Cause Cancer
Venton, B. Jill
Analytical Neurochemistry; Dopamine and Serotonin Neurotransmission in Drosophila; Mechanisms of rapid adenosine signaling in rodents
Witt, Russell Gardner
Unraveling the Role of Obesity, Diet, and Lifestyle Factors in Melanoma Progression and Treatment Efficacy
Yates, Paul A.
Development and regulation of retinal ganglion cells (RGCs) and blood vessels as they relate to retinal diseases.
Zimring, James C
Alloimmunity in Transfusion and Transplantation , Oxidant Stress Biology in Health and Disease