The Cell Biology program provides outstanding training of PhD candidates in a vibrant and rapidly evolving field. Our comprehensive program emphasizes original research, interdisciplinary coursework, and advanced topical colloquia. Trainees have the opportunity to explore fundamental questions in many areas including molecular mechanisms of cell function; regulation of growth and differentiation; cell interactions in migration; embryonic patterning in development; and morphogenesis of cells, tissues and organs. Training in cell and developmental biology forms the basis not only for making fundamental new discoveries, but also for understanding and exploring the links to human diseases where the fundamental processes of cytoskeletal dynamics, membrane trafficking, signal transduction, mitosis, cell adhesion, motility, mechanotransduction, and polarity go awry. For more information, click here…
Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Bloom, George S.
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
Casanova, James E.
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.
Chalfant, Charles Edward
Hematology and Oncology, Cell Biology, Lipid Signaling, Cancer Cell Signaling, and RNA Biology
Adult-born neurons, perineuronal nets, and microglia in hippocampal plasticity and behavior in health and disease
Neuron-glia and glial-glial interactions
DeSimone, Douglas W.
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis
Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance
Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging
Halme, Adrian J.
Regeneration and Systemic Responses to Tissue Damage
Hinton, Barry T.
Morphogenesis of the Developing Wolffian/Epididymal duct
Hirschi, Karen Kemper
Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation
Kashatus, David F
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Keller, Raymond E.
Cellular and molecular mechanisms of morphogenesis
Kozminski, Keith G.
Regulation of Polarized Morphogenesis
Kucenas, Sarah C.
The role of glia in the development, maintenance and regeneration of the nervous system
Precision medicine, translational science, regeneration, organoids, high resolution imaging, computational modeling
Kuyumcu-Martinez, Muge N
RNA regulatory networks and RNA binding proteins during cardiovascular development and in cardiovascular disease
Laurie, Gordon W.
Restoration of Homeostasis in Disease
Wnt/PCP signaling in inner ear development Mouse models for human deafness Wnt/PCP signaling in neural tube closure
O’Rourke, Eyleen Jorgelina
Obesity and Aging
Investigating the cell-biological foundations of development
Developmental Genetics, Evolution and Regeneration
Mechanisms of tissue/organ homeostasis and tumorigeensis
Chromosome segregation and aneuploidy in meiosis and mitosis
Sheynkman, Gloria M.
Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease
Regulation of neural stem cell proliferation during development and adulthood
Spiliotis, Elias T
Spatial Cell Biology. Neuronal Morphogenesis and Disease. Cancer Migration and Invasion.
Stukenberg, P. Todd
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors
Sutherland, Ann E.
Cell behavior and morphogenesis during early mouse development.
Regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells
Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.
Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling
Zeitlin, Scott O.
Mechanisms of Huntington's Disease Pathogenesis
Early detection, cancer prevention, and tumor microenvironment