Research Projects & Trials


  • Systemic and cardiac complications of seizures and status epilepticus in the Epilepsy Monitoring Unit and the NeuroICU.
  • Using quantitative EEG markers and physiologic measurements to predict neurologic outcomes after cardiac arrest.
  • Analysis of multiple physiologic data to predict vasospasm in subarachnoid hemorrhage.
  • Established Epilepticus Treatment Trial (ESETT): determining the second-line drug therapy for status epilepticus.
  • Rotational Thromboelastometry for Monitoring the Effect of Prothrombin Complex Concentrate for Coagulopathy Reversal in Patients with Warfarin-Associated Intracerebral Hemorrhage.
  • Riluzole in Spinal Cord Injury Study (RISCIS): A Multi-Center, Randomized, Placebo Controlled, Double-Blinded, Trial of Efficacy and Safety of Riluzole in Acute Spinal Cord Injury
  • Inmate inflammation in Subarachnoid hemorrhage (SAH).

  • The INSPIRE Study: InVivo Study of Probable Benefit of the Neuro-Spinal ScaffoldTM for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury
  • MISTIE-III: A phase III, randomized, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage.
  • The DECS Trial: Dexamethasone Versus Burr Hole Craniostomy for Symptomatic Chronic Subdural Hematoma.
  • SHINE Trial: The Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial is a multicenter, randomized, controlled clinical trial of 1400 patients that will include approximately 60 enrolling sites. The study hypotheses are that treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL – 130 mg/dL) will be safe and result in improved 3 month outcome after stroke.

For a full list of clinical trials at UVA, please visit the following website: