Christopher P. Holstege, MD

HolstegeCProfessor of Emergency Medicine and Pediatrics
Chief, Division of Medical Toxicology
Executive Director, Elson Student Health Center
Director, Blue Ridge Poison Center

P.O. Box 800699
Charlottesville, VA 22908-0699
Phone: (434) 924-5185
Fax: (434) 971-8657



  • Fellowship, Medical Toxicology, Indiana University (1998)
  • Residency, Emergency Medicine, Butterworth Hospital (1996)
  • MD, Wayne State University School of Medicine (1993)
  • BS, Chemistry, Calvin College (1988)

Clinical and Research Interests

  • Clinical Toxicology
  • Chemical agents utilized in terrorism/murder
  • Substance abuse trends in the student populations
  • Emergence of new substances of abuse


  • Jennifer A Ross, MD, MPH, Christopher P Holstege, MD, Comment on “Effects of Acetaminophen on Risk Taking”, Social Cognitive and Affective Neuroscience, 2021;, nsab025,
  • Jennifer A. Ross & Christopher P. Holstege (2021) Comment on Seizure in venlafaxine overdose: a 10-year retrospective review of the California poison control system, Clinical Toxicology, DOI: 10.1080/15563650.2020.1870124
  • Holstege C, Ngo DA, Borek H, Ait-Daoud N, Davis S, Rege S. Trends and risk markers of student hazardous drinking: a comparative analysis using longitudinally linked datasets in a public university. J Am Coll Health. 2020 Oct 13:1-8. doi: 10.1080/07448481.2020.1818755. Epub ahead of print. PMID: 33048653.
  • Snyder MH, Ross JA, Rege SV, Holstege CP. Comment on “Pediatric guanfacine exposures reported to the National Poison Data System, 2000-2016”. Clin Toxicol (Phila). 2020 Nov 2:1. doi: 10.1080/15563650.2020.1837387. Epub ahead of print. PMID: 33135517.
  • Jennifer A. Ross, MD; John W. Downs, MD; Lindsay A. Bazydlo, PhD; Paige H. Bordwine, MPH; Catherine E. Gineste, PhD; Marissa C. Kopatic, MD; Saumitra V. Rege, PhD; Dawn M. Saady, MS; Okey F. Utah, MBBS; Shane A. Wyatt; Brandon K. Wills, DO; S. Rutherfoord Rose, PharmD; Christopher Holstege, MD. Outbreak of Severe Hypoglycemia After Ingestion of a Male Enhancement Supplement — Virginia, August–November 2019. MMWR Morb Mortal Wkly Rep 2020;69:740–743. DOI:
  • Michael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, Michael C. Beuhler, D. Adam Algren & Christopher P. Holstege (2020) Comment on “Transition to two-bag intravenous acetylcysteine for acetaminophen overdose”, Clinical Toxicology, 58:5,433-435, DOI: 10.1080/15563650.2019.1649418
  • Rege SV, Borek H, Holstege CP. Response to Do Patients Require Emergency Department Interventions After Prehospital Naloxone? J Addict Med. 2020 Aug 12. doi:10.1097/ADM.0000000000000715. Epub ahead of print. PMID: 32804692.
  • Saumitra V. Rege, Duc Anh Ngo, Nassima Ait-Daoud, Justin Rizer, Sana Sharma, Christopher P. Holstege, Epidemiology of pediatric buprenorphine and methadone exposures reported to the poison centers, Annals of Epidemiology, Volume 42, 2020, Pages 50-57.e2,ISSN 1047-2797,