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Department of Pathology

Katia Sol-Church, Ph.D.

 

Katia Sol-Church, Ph.D.

Research Professor of Pathology
Director of Genome Analysis & Technology Core
Office of Research Core Administration

EDUCATION:

Doctorate Degree: Doctoral Degree, McGill University, Montreal Canada

Masters Degree: Cellular Biology Université Paul Sabatier, Toulouse, France

CLINICAL:

Rasopathies and cancer predisposition syndromes; personalized medicine/clinical genomics

RESEARCH:

As Director of the UVA genomics core my focus is to apply omics technologies to advance biomedical research excellence and support rigor and reproducibility in science. As a team leader at Nemours I have discovered the causes of several rare genetic disorders including RASopathies and other cancer predisposition syndromes.

PUBLICATIONS:

  1. Turner AW, Hu SS, Mosquera JV, Ma WF, Hodonsky CJ, Wong D, Auguste G, Song Y, Sol-Church K, Farber E, Kundu S, Kundaje A, Lopez NG, Ma L, Ghosh SKB, Onengut-Gumuscu S, Ashley EA, Quertermous T, Finn AV, Leeper NJ, Kovacic JC, Björkegren JLM, Zang C, Miller CL. Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk Nat Genet. 2022 Jun;54(6):804-816. doi: 10.1038/s41588-022-01069-0. Epub 2022 May 19. PMID: 35590109
  2. T. Morlet, KM. Robbins, D. Stabley, J. Holbrook, K. Sol-Church and RC. O’Reilly Mutations in LOXHD1 gene can cause auditory neuropathy spectrum disorder Otolaryngology Case Reports, 2021-11-01, Volume 21
  3. Melssen MM, Pollack KE, Meneveau MO, Smolkin ME, Pinczewski J, Koeppel AF, Turner SD, Sol-Church K, Hickman A, Deacon DH, Petroni GR, Slingluff CL Jr. Characterization and comparison of innate and adaptive immune responses at vaccine sites in melanoma vaccine clinical trials. Cancer Immunol Immunother. 2021 Jan 16;. doi: 10.1007/s00262-020-02844-w. [Epub ahead of print] PubMed PMID: 33454795.
  4. Pollack KE, Meneveau MO, Melssen MM, Lynch KT, Koeppel AF, Young SJ, Turner S, Kumar P, Sol-Church K, Mauldin IS, Slingluff CL Jr. Incomplete Freund’s adjuvant reduces arginase and enhances Th1 dominance, TLR signaling and CD40 ligand expression in the vaccine site microenvironment. J Immunother Cancer. 2020 Apr;8(1):e000544. doi: 10.1136/jitc-2020-000544. PMID: 32350119
  5. Mische SM, Fisher NC, Meyn SM, Sol-Church K, Hegstad-Davies RL, Weis-Garcia F, Adams M, Ashton JM, Delventhal KM, Dragon JA, Holmes L, Jagtap P, Kubow KE, Mason CE, Palmblad M, Searle BC, Turck CW, Knudtson KL. A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups. J Biomol Tech. 2020 Apr;31(1):11-26. doi: 10.7171/jbt.20-3101-003. PMID: 31969795
  6. Knudtson KL, Carnahan RH, Hegstad-Davies RL, Fisher NC, Hicks B, Lopez PA, Meyn SM, Mische SM, Weis-Garcia F, White LD, Sol-Church K. Survey on Scientific Shared Resource Rigor and Reproducibility Version 2. J Biomol Tech. 2019 Sep;30(3):36-44. doi: 10.7171/jbt.19-3003-001 PMID: 31452645.
  7. Operario DJ, Pholwat S, Koeppel AF, Prorock A, Bao Y, Sol-Church K, Scheurenbrand M, Poulter M, Turner S, Parikh HI, Mathers A, Houpt ER. Mycobacterium avium Complex Diversity within Lung Disease, as Revealed by Whole-Genome Sequencing. Am J Respir Crit Care Med. 2019 Aug 1;200(3):393-396. doi: 10.1164/rccm.201903-0669LE. PMID: 30965019.
  8. LaCroix AJ, Stabley D, Sahraoui R, Adam MP, Mehaffey M, Kernan K, Myers CT, Fagerstrom C, Anadiotis G, Akkari YM, Robbins KM, Gripp KW, Baratela WAR, Bober MB, Duker AL, Doherty D, Dempsey JC, Miller DG, Kircher M, Bamshad MJ, Nickerson DA; University of Washington Center for Mendelian Genomics, Mefford HC, Sol-Church K. GGC Repeat Expansion and Exon 1 Methylation of XYLT1 Is a Common Pathogenic Variant in Baratela-Scott Syndrome  Am J Hum Genet. 2019 Jan 3;104(1):35-44. doi: 10.1016/j.ajhg.2018.11.005. Epub 2018 Dec 13. PMID: 30554721.
  9. Cartledge DM, Robbins KM, Drake KM, Sternberg R, Stabley DL, Gripp KW, Kolb EA, Sol-Church K, Napper AD. “Selective cytotoxicity of zardaverine in embryonal rhabdomyosarcoma from a Costello syndrome patient”  Front Oncol. 2017 Apr 3;7:42. doi: 10.3389/fonc.2017.00042. eCollection 2017.PMID: 28421158
  10. Stabley DL, Holbrook J, Harris AW, Swoboda KJ, Crawford TO, Sol-Church K, Butchbach ME. “Establishing a reference dataset for the authentication of spinal muscular atrophy cell lines using STR profiling and digital PCR” Neuromuscul Disord. 2017 Feb 6. pii: S0960-8966(16)31158-0. doi: 10.1016/j.nmd.2017.02.002. [Epub ahead of print] PMID: 28284873
  11. Higgins EM, Bos JM, Mason-Suares H, Tester DJ, Ackerman JP, MacRae CA, Sol-Church K, Gripp KW, Urrutia R, Ackerman MJ. “Elucidation of MRAS-Mediated Noonan Syndrome  JCI Insight. 2017 Mar 9;2(5):e91225. doi: 10.1172/jci.insight.91225. PMID: 28289718
  12. Schwartz DD, Katzenstein JM, Highley EJ, Stabley DL, Sol-Church K, Gripp KW, Axelrad ME. “Age-Related Differences in Prevalence of Autism Spectrum Disorder Symptoms in Children and Adolescents with Costello Syndrome”. Am J Med Genet A. 2017 Apr 4. doi: 10.1002/ajmg.a.38174. [Epub ahead of print] PMID: 28374929
  13. Bertola D, Buscarilli M, Stabley DL, Baker L, Doyle D, Bartholomew DW, Sol-Church K, Gripp KW. “Phenotypic Spectrum of Costello Syndrome Individuals Harboring the Rare HRAS Mutation p.Gly13Asp” Am J Med Genet A. 2017 Apr 3. doi: 10.1002/ajmg.a.38178. [Epub ahead of print] PMID: 28371260
  14. Wang Y, Li J, Kolon TF, Olivant Fisher A, Figueroa TE, BaniHani AH, Hagerty JA, Gonzalez R, Noh PH, Chiavacci RM, Harden KR, Abrams DJ, Stabley D, Kim CE, Sol-Church K, Hakonarson H, Devoto M, Barthold JS. Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism. BMC Urol. 2016 Oct 21;16(1):62. PMID: 27769252; PubMed Central PMCID: PMC5073740.
  15. Robbins KM, Stabley DL, Holbrook J, Sahraoui R, Sadreameli A Conard K, Baker L, Gripp KW, Sol-Church K. Paternal uniparental disomy with segmental loss of heterozygosity of chromosome 11 are hallmark characteristics of syndromic and sporadic embryonal rhabdomyosarcoma. Am J Med Genet A. 2016 Sep 2; PMID: 27589201.
  16. Gripp KW, Aldinger KA, Bennett JT, Baker L, Tusi J, Powell-Hamilton N, Stabley D, Sol-Church K, Timms AE, Dobyns WB. A novel rasopathy caused by recurrent de novo missense mutations in PPP1CB closely resembles Noonan syndrome with loose anagen hair. Am J Med Genet A. 2016 Sep;170(9):2237-47. PubMed PMID: 27264673.
  17. Gripp KW, Robbins KM, Sheffield BS, Lee AF, Patel MS, Yip S, Doyle D, Stabley D, Sol-Church K.. Paternal uniparental disomy 11p155 in the pancreatic nodule of an infant with Costello syndrome: Shared mechanism for hyperinsulinemic hypoglycemia in neonates with Costello and Beckwith-Wiedemann syndrome and somatic loss of heterozygosity in Costello syndrome driving clonal expansion. Am J Med Genet A. 2016 Mar;170(3):559-64. PubMed PMID: 26572961; NIHMSID: NIHMS757008; PubMed Central PMCID: PMC4784973.
  18. Koenighofer M, Hung CY, McCauley JL, Dallman J, Back EJ, Mihalek I, Gripp KW, Sol-Church K, Rusconi P, Zhang Z, Shi GX, Andres DA, Bodamer OA Mutations in RIT1 cause Noonan syndrome – additional functional evidence and expanding the clinical phenotype. Clin Genet. 2016 Mar;89(3):359-66. PubMed PMID: 25959749; NIHMSID: NIHMS694165; PubMed Central PMCID: PMC4760689.
  19. Barthold JS, Pugarelli J, MacDonald ML, Ren J, Adetunji MO, Polson SW, Mateson A, Wang Y, Sol-Church K, McCahan SM, Akins RE Jr, Devoto M, Robbins AK. Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat. Mol Hum Reprod. 2016 Jan;22(1):18-34. PubMed PMID: 26502805; PubMed Central PMCID: PMC4694052.
  20. Gripp KW, Sol-Church K, Smpokou P, Graham GE, Stevenson DA, Hanson H, Viskochil DH, Baker LC, Russo B, Gardner N, Stabley DL, Kolbe V, Rosenberger GAn attenuated phenotype of Costello syndrome in three unrelated individuals with a HRAS c179G>A (pGly60Asp) mutation correlates with uncommon functional consequences. Am J Med Genet A. 2015 Sep;167A(9):2085-97. PubMed PMID: 25914166; NIHMSID: NIHMS775287; PubMed Central PMCID: PMC4830354.
  21. Stabley DL, Harris AW, Holbrook J, Chubbs NJ, Lozo KW, Crawford TO, Swoboda KJ, Funanage VL, Wang W, Mackenzie W, Scavina M, Sol-Church K, Butchbach ME. SMN1 and SMN2 copy numbers in cell lines derived from patients with spinal muscular atrophy as measured by array digital PCR. Mol Genet Genomic Med. 2015 Jul;3(4):248-57. PubMed PMID: 26247043; PubMed Central PMCID: PMC4521962.
  22. Niceta M, Stellacci E, Gripp KW, Zampino G, Kousi M, Anselmi M, Traversa A, Ciolfi A, Stabley D, Bruselles A, Caputo V, Cecchetti S, Prudente S, Fiorenza MT, Boitani C, Philip N, Niyazov D, Leoni C, Nakane T, Keppler-Noreuil K, Braddock SR, Gillessen-Kaesbach G, Palleschi A, Campeau PM, Lee BH, Pouponnot C, Stella L, Bocchinfuso G, Katsanis N, Sol-Church K, Tartaglia M. Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like Facies. Am J Hum Genet. 2015 May 7;96(5):816-25. PubMed PMID: 25865493; PubMed Central PMCID: PMC4570552.
  23. Kolb EA, Sampson V, Stabley D, Walter A, Sol-Church K, et al. A phase I trial and viral clearance study of reovirus (Reolysin) in children with relapsed or refractory extra-cranial solid tumors: a Children’s Oncology Group Phase I Consortium report. Pediatr Blood Cancer. 2015 May;62(5):751-8. PubMed PMID: 25728527; NIHMSID: NIHMS658111; PubMed Central PMCID: PMC4376570.
  24. Crowgey EL, Stabley DL, Chen C, Huang H, Robbins KM, Polson SW, Sol-Church K, Wu CH An integrated approach for analyzing clinical genomic variant data from next-generation sequencing. J Biomol Tech. 2015 Apr;26(1):19-28. PubMed PMID: 25649353; PubMed Central PMCID: PMC4310222.
  25. Gripp KW, Robbins KM, Sobreira NL, Witmer PD, Bird LM, Avela K, Makitie O, Alves D, Hogue JS, Zackai EH, Doheny KF, Stabley DL, Sol-Church K Truncating mutations in the last exon of NOTCH3 cause lateral meningocele syndrome. Am J Med Genet A. 2015 Feb;167A(2):271-81. PubMed PMID: 25394726.
  26. Weaver KN, Wang D, Cnota J, Gardner N, Stabley D, Sol-Church K, Gripp KW, Witte DP, Bove KE, Hopkin RJ  Early-lethal Costello syndrome due to rare HRAS Tandem Base substitution (c35_36GC>AA; pG12E)-associated pulmonary vascular disease. Pediatr Dev Pathol. 2014 Nov-Dec;17(6):421-30. PubMed PMID: 25133308; NIHMSID: NIHMS625678; PubMed Central PMCID: PMC4294968.
  27. Gripp KW, Curry C, Olney AH, Sandoval C, Fisher J, Chong JX, Pilchman L, Sahraoui R, Stabley DL, Sol-Church K. Diamond-Blackfan anemia with mandibulofacial dystostosis is heterogeneous, including the novel DBA genes TSR2 and RPS28. Am J Med Genet A. 2014 Sep;164A(9):2240-9. PubMed PMID: 24942156; NIHMSID: NIHMS599316; PubMed Central PMCID: PMC4149220.
  28. Gripp KW, Zand DJ, Demmer L, Anderson CE, Dobyns WB, Zackai EH, Denenberg E, Jenny K, Stabley DL, Sol-Church K.  Expanding the SHOC2 mutation associated phenotype of Noonan syndrome with loose anagen hair: structural brain anomalies and myelofibrosis. Am J Med Genet A. 2013 Oct;161A(10):2420-30. PubMed PMID: 23918763; NIHMSID: NIHMS491306; PubMed Central PMCID: PMC3787995.
  29. Schwartz DD, Katzenstein JM, Hopkins E, Stabley DL, Sol-Church K, Gripp KW, Axelrad ME Verbal memory functioning in adolescents and young adults with Costello syndrome: evidence for relative preservation in recognition memory. Am J Med Genet A. 2013 Sep;161A(9):2258-65. PubMed PMID: 23918324; NIHMSID: NIHMS483456; PubMed Central PMCID: PMC3745536.
  30. McCormick EM, Hopkins E, Conway L, Catalano S, Hossain J, Sol-Church K, Stabley DL, Gripp KW l. Assessing genotype-phenotype correlation in Costello syndrome using a severity score. Genet Med. 2013 Jul;15(7):554-7. PubMed PMID: 23429430.
  31. Sammon MR, Doyle D, Hopkins E, Sol-Church K, Stabley DL, et al. Normative growth charts for individuals with Costello syndrome. Am J Med Genet A. 2012 Nov;158A(11):2692-9. PubMed PMID: 22887473.
  32. Gripp KW, Bifeld E, Stabley DL, Hopkins E, Meien S, Vinette K, Sol-Church K, Rosenberger G. A novel HRAS substitution (c266C>G; pS89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development. Am J Med Genet A. 2012 Sep;158A(9):2106-18. PubMed PMID: 22821884; NIHMSID: NIHMS625759; PubMed Central PMCID: PMC4166655.
  33. Baratela WA, Bober MB, Tiller GE, Okenfuss E, Ditro C, Duker A, Krakow D, Stabley DL, Sol-Church K, Mackenzie W, Lachman R, Scott CI Jr. A newly recognized syndrome with characteristic facial features, skeletal dysplasia, and developmental delay. Am J Med Genet A. 2012 Aug;158A(8):1815-22. PubMed PMID: 22711505; NIHMSID: NIHMS626895; PubMed Central PMCID: PMC4164294.
  34. Gripp KW, Hopkins E, Serrano A, Leonard NJ, Stabley DL, Sol-Church K. Transmission of the rare HRAS mutation (c 173C > T; pT58I) further illustrates its attenuated phenotype. Am J Med Genet A. 2012 May;158A(5):1095-101. PubMed PMID: 22488832; NIHMSID: NIHMS626887; PubMed Central PMCID: PMC4164267.
  35. Mage DT, Donner ME, Vennemann M, Fleming P, Sol-Church K, Drake R, Gulino SP. All sudden unexplained infant respiratory deaths may result from the same underlying mechanism. Scand J. of Forensic Science. 2012; 18(1):1-9. No PMC
  36. Doyle D, Kirwin SM, Sol-Church K, Levine MA. A novel mutation in the GCM2 gene causing severe congenital isolated hypoparathyroidism. J Pediatr Endocrinol Metab. 2012;25(7-8):741-6. PubMed PMID: 23155703; NIHMSID: NIHMS478837; PubMed Central PMCID: PMC3694175.
  37. Gripp KW, Stabley DL, Geller PL, Hopkins E, Stevenson DA, Carey JC, Sol-Church K. Molecular confirmation of HRAS pG12S in siblings with Costello syndrome. Am J Med Genet A. 2011 Sep;155A(9):2263-8. PubMed PMID: 21834037; NIHMSID: NIHMS301505; PubMed Central PMCID: PMC3158836.
  38. Allanson JE, Annerén G, Aoki Y, Armour CM, Bondeson ML, Cave H, Gripp KW, Kerr B, Nystrom AM, Sol-Church K, Verloes A, Zenker M. Cardio-facio-cutaneous syndrome: does genotype predict phenotype?. Am J Med Genet C Semin Med Genet. 2011 May 15;157C(2):129-35. PubMed PMID: 21495173; NIHMSID: NIHMS282899; PubMed Central PMCID: PMC3086095.
  39. Gripp KW, Hopkins E, Sol-Church K, Stabley DL, Axelrad ME, et al. Phenotypic analysis of individuals with Costello syndrome due to HRAS pG13C. Am J Med Genet A. 2011 Apr;155A(4):706-16. PubMed PMID: 21438134; NIHMSID: NIHMS626891; PubMed Central PMCID: PMC4166651.
  40. Lin AE, Alexander ME, Colan SD, Kerr B, Rauen KA, Noonan J, Baffa J, Hopkins E, Sol-Church K, Limongelli G, Digilio MC, Marino B, Innes AM, Aoki Y, Silberbach M, Delrue MA, White SM, Hamilton RM, O’Connor W, Grossfeld PD, Smoot LB, Padera RF, Gripp KW. Clinical, pathological, and molecular analyses of cardiovascular abnormalities in Costello syndrome: a Ras/MAPK pathway syndrome. Am J Med Genet A. 2011 Mar;155A(3):486-507. PubMed PMID: 21344638.
  41. Papadopoulou E, Sifakis S, Sol-Church K, Klein-Zighelboim E, Stabley DL, et al. CNS imaging is a key diagnostic tool in the evaluation of patients with CFC syndrome: two cases and literature review. Am J Med Genet A. 2011 Mar;155A(3):605-11. PubMed PMID: 21337689.
  42. Hopkins E, Lin AE, Krepkovich KE, Axelrad ME, Sol-Church K, et al. Living with Costello syndrome: quality of life issues in older individuals. Am J Med Genet A. 2010 Jan;152A(1):84-90. PubMed PMID: 20034064.
  43. Axelrad ME, Schwartz DD, Fehlis JE, Hopkins E, Stabley DL, Sol-Church K, Gripp KW Longitudinal course of cognitive, adaptive, and behavioral characteristics in Costello syndrome. Am J Med Genet A. 2009 Dec;149A(12):2666-72. PubMed PMID: 19919001; NIHMSID: NIHMS146520; PubMed Central PMCID: PMC2787985.
  44. Lin AE, O’Brien B, Demmer LA, Almeda KK, Blanco CL, Glasow PF, Berul CI, Hamilton R, Micheil Innes A, Lauzon JL, Sol-Church K, Gripp KW.. Prenatal features of Costello syndrome: ultrasonographic findings and atrial tachycardia. Prenat Diagn. 2009 Jul;29(7):682-90. PubMed PMID: 19382114; NIHMSID: NIHMS128855; PubMed Central PMCID: PMC4293073.
  45. Sol-Church K, Stabley DL, Demmer LA, Agbulos A, Lin AE, Smoot L, Nicholson L, Gripp KW Male-to-male transmission of Costello syndrome: G12S HRAS germline mutation inherited from a father with somatic mosaicism. Am J Med Genet A. 2009 Mar;149A(3):315-21. PubMed PMID: 19206176; NIHMSID: NIHMS85441; PubMed Central PMCID: PMC2653086.
  46. Zhang H, Sol-Church K, Rydbeck H, Stabley D, Spotila LD, Devoto M. High resolution linkage and linkage disequilibrium analyses of chromosome 1p36 SNPs identify new positional candidate genes for low bone mineral density. Osteoporos Int. 2009 Feb;20(2):341-6. PubMed PMID: 18597038.
  47. Cooper CR, Graves B, Pruitt F, Chaib H, Lynch JE, Cox AK, Sequeria L, van Golen KL, Evans A, Czymmek K, Bullard RS, Donald CD, Sol-Church K, Gendernalik JD, Weksler B, Farach-Carson MC, Macoska JA, Sikes RA, Pienta KJ.. Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha. J Cell Biochem. 2008 Aug 15;104(6):2298-309. PubMed PMID: 18561328.
  48. Gripp KW, Innes AM, Axelrad ME, Gillan TL, Parboosingh JS, Davies C, Leonard NJ, Lapointe M, Doyle D, Catalano S, Nicholson L, Stabley DL, Sol-Church K Costello syndrome associated with novel germline HRAS mutations: an attenuated phenotype? Am J Med Genet A. 2008 Mar 15;146A(6):683-90. PubMed PMID: 18247425.
  49. Axelrad ME, Nicholson L, Stabley DL, Sol-Church K, Gripp KW. Longitudinal assessment of cognitive characteristics in Costello syndrome. Am J Med Genet A. 2007 Dec 15;143A(24):3185-93. PubMed PMID: 17963256.
  50. Al-Rahawan MM, Chute DJ, Sol-Church K, Gripp KW, Stabley DL, et al. Hepatoblastoma and heart transplantation in a patient with cardio-facio-cutaneous syndrome. Am J Med Genet A. 2007 Jul 1;143A(13):1481-8. PubMed PMID: 17567882.
  51. Gripp KW, Lin AE, Nicholson L, Allen W, Cramer A, Jones KL, Kutz W, Peck D, Rebolledo MA, Wheeler PG, Wilson W, Al-Rahawan MM, Stabley DL, Sol-Church K Further delineation of the phenotype resulting from BRAF or MEK1 germline mutations helps differentiate cardio-facio-cutaneous syndrome from Costello syndrome. Am J Med Genet A. 2007 Jul 1;143A(13):1472-80. PubMed PMID: 17551924.
  52. Ioannidis JP, Ng MY, Sham PC, Zintzaras E, Lewis CM, Deng HW, Econs MJ, Karasik D, Devoto M, Kammerer CM, Spector T, Andrew T, Cupples LA, Duncan EL, Foroud T, Kiel DP, Koller D, Langdahl B, Mitchell BD, Peacock M, Recker R, Shen H, Sol-Church K, Spotila LD, Uitterlinden AG, Wilson SG, Kung AW, Ralston SH.. Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res. 2007 Feb;22(2):173-83. PubMed PMID: 17228994; NIHMSID: NIHMS576477; PubMed Central PMCID: PMC4016811.
  53. Gripp KW, Stabley DL, Nicholson L, Hoffman JD, Sol-Church K. Somatic mosaicism for an HRAS mutation causes Costello syndrome. Am J Med Genet A. 2006 Oct 15;140(20):2163-9. PubMed PMID: 16969868.
  54. Barthold JS, Si X, Stabley D, Sol-Church K, Campion L, McCahan SM Failure of shortening and inversion of the perinatal gubernaculum in the cryptorchid long-evans orl rat. J Urol. 2006 Oct;176(4 Pt 1):1612-7. PubMed PMID: 16952701.
  55. Sol-Church K, Stabley DL, Nicholson L, Gonzalez IL, Gripp KW. Paternal bias in parental origin of HRAS mutations in Costello syndrome. Hum Mutat. 2006 Aug;27(8):736-41. PubMed PMID: 16835863.
  56. Zhang H, Barnoski BL, Sol-Church K, Stabley DL, Martin-Deleon PA. Murine Spam1 mRNA: involvement of AU-rich elements in the 3’UTR and antisense RNA in its tight post-transcriptional regulation in spermatids. Mol Reprod Dev. 2006 Feb;73(2):247-55. PubMed PMID: 16250006.
  57. Gripp KW, Lin AE, Stabley DL, Nicholson L, Scott CI Jr, Doyle D, Aoki Y, Matsubara Y, Zackai EH, Lapunzina P, Gonzalez-Meneses A, Holbrook J, Agresta CA, Gonzalez IL, Sol-Church K HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation. Am J Med Genet A. 2006 Jan 1;140(1):1-7. PubMed PMID: 16329078.
  58. Holbrook JF, Stabley D, Sol-Church K. Exploring whole genome amplification as a DNA recovery tool for molecular genetic studies. J Biomol Tech. 2005 Jun;16(2):125-33. PubMed PMID: 16030319; PubMed Central PMCID: PMC2291715.
  59. Devoto M, Spotila LD, Stabley DL, Wharton GN, Rydbeck H, Korkko J, Kosich R, Prockop D, Tenenhouse A, Sol-Church K.l. Univariate and bivariate variance component linkage analysis of a whole-genome scan for loci contributing to bone mineral density. Eur J Hum Genet. 2005 Jun;13(6):781-8. PubMed PMID: 15827564.
  60. Mason RW, Bergman CA, Lu G, Frenck Holbrook J, Sol-Church K. Expression and characterization of cathepsin P. Biochem J. 2004 Mar 1;378(Pt 2):657-63. PubMed PMID: 14629193; PubMed Central PMCID: PMC1223977.
  61. Mason RW, Stabley DL, Picerno GN, Frenck J, Xing S, Bertenshaw GP, Sol-Church K Evolution of placental proteases. Biol Chem. 2002 Jul-Aug;383(7-8):1113-8. PubMed PMID: 12437094.
  62. Sol-Church K, Picerno GN, Stabley DL, Frenck J, Xing S, et al. Evolution of placentally expressed cathepsins. Biochem Biophys Res Commun. 2002 Apr 26;293(1):23-9. PubMed PMID: 12054558.
  63. Sol-Church K, Frenck J, Bertenshaw G, Mason RW. Characterization of mouse cathepsin R, a new member of a family of placentally expressed cysteine proteases. Biochim Biophys Acta. 2000 Jul 24;1492(2-3):488-92. PubMed PMID: 11004518.
  64. Sol-Church K, Frenck J, Mason RW. Mouse cathepsin M, a placenta-specific lysosomal cysteine protease related to cathepsins L and P. Biochim Biophys Acta. 2000 Apr 25;1491(1-3):289-94. PubMed PMID: 10760593.
  65. Sol-Church K, Frenck J, Mason RW. Cathepsin Q, a novel lysosomal cysteine protease highly expressed in placenta. Biochem Biophys Res Commun. 2000 Jan 27;267(3):791-5. PubMed PMID: 10673370.
  66. Sol-Church K, Shipley J, Beckman DA, Mason RW. Expression of cysteine proteases in extraembryonic tissues during mouse embryogenesis. Arch Biochem Biophys. 1999 Dec 15;372(2):375-81. PubMed PMID: 10600178.
  67. Sol-Church K, Frenck J, Troeber D, Mason RW. Cathepsin P, a novel protease in mouse placenta. Biochem J. 1999 Oct 15;343 Pt 2:307-9. PubMed PMID: 10510293; PubMed Central PMCID: PMC1220554.
  68. Mason RW, Sol-Church K, Abrahamson M. Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases. Biochem J. 1998 Mar 1;330 (Pt 2):833-8. PubMed PMID: 9480898; PubMed Central PMCID: PMC1219213.
  69. Sol K, DuBow MS. Sequence analysis of cloned human satellite DNAs reveals nonrandom variations. Genome. 1993 Apr;36(2):334-42. PubMed PMID: 8514158.
  70. Sol K, DuBow MS. Structure and organization of a human EcoR1 satellite II DNA family. Molecular Biology. 1991; 11:159-168. No PMC
  71. Sol K, Lapointe M, MacLeod M, Nadeau C, DuBow MS. A cloned fragment of HeLa DNA containing consensus sequences of satellite II and III DNA hybridizes with the Drosophila P-element and with the 18 kb family of human KpnI fragments. Biochim Biophys Acta. 1986 Nov 13;868(2-3):128-35. PubMed PMID: 3021224.

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